Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

The PEA3 subfamily is a subgroup of the E26 transformation-specific (ETS) family. Its
members, ETV1, ETV4, and ETV5, have been found to be overexpressed in multiple …

Gastric cancer has remained in the top five cancers for over ten years, both in terms of
incidence and mortality due to the shortage of biomarkers for disease follow-up and effective …

Aims Gastric cancer stem cells (GCSCs) have been used as a therapeutic target. This study
aims to estimate the role of miR-98-5p (termed miR-98) in the development of GCSCs. Main …

The antibody-drug conjugates (ADCs) are one the fastest growing biotherapeutics in
oncology and are still in their infancy in gastrointestinal (GI) cancer for clinical applications to …

Recently, radioresistant cancer cells surviving radiotherapy have been suggested to show
more aggressive phenotypes than parental cells, and the underlying mechanisms may be …

A long noncoding RNA (lncRNA) transcript is generally more than 200 nucleotides in length
and rarely codes for any protein. Currently, many lncRNAs have been identified among …

Cancer is a major disease that endangers human health. Cancer drug resistance and
relapse are the two main causes contributing to cancer treatment failure. Cancer stem cells …

As a relatively rare population of cancer cells existing in the tumor microenvironment, cancer
stem cells (CSCs) possess properties of immune privilege to evade the attack of immune …

The progress of cancer treatment methods in the last decade has significantly reduced
mortality rate among these patients. Nevertheless, cancer is still recognized as one of the …