Fibrin is a protein polymer that is essential for hemostasis and thrombosis, wound healing, and several other biological functions and pathological conditions that involve extracellular …
Fibrin is a protein polymer that forms a 3D filamentous network, a major structural component of protective physiological blood clots as well as life threatening pathological …
DB Kell, E Pretorius - Progress in biophysics and molecular biology, 2017 - Elsevier
The chief and largely terminal element of normal blood clotting is considered to involve the polymerisation of the mainly α-helical fibrinogen to fibrin, with a binding mechanism …
E Mihalko, AC Brown - Seminars in thrombosis and hemostasis, 2020 - thieme-connect.com
The formation of a fibrin clot matrix plays a critical role in promoting hemostasis and wound healing. Fibrin dynamics can become disadvantageous in the formation of aberrant …
X Wang, T Friis, V Glatt, R Crawford… - Journal of tissue …, 2017 - Wiley Online Library
Blood clots (haematomas) that form immediately following a bone fracture have been shown to be vital for the subsequent healing process. During the clotting process, a number of …
F Fleissner, M Bonn, SH Parekh - Science advances, 2016 - science.org
Following an injury, a blood clot must form at the wound site to stop bleeding before skin repair can occur. Blood clots must satisfy a unique set of material requirements; they need to …
Mechanical properties have been extensively studied in pure elastic or viscous materials; however, most biomaterials possess both physical properties in a viscoelastic component …
J Xia, LH Cai, H Wu… - Proceedings of the …, 2021 - National Acad Sciences
Fibrin is the main component of blood clots. The mechanical properties of fibrin are therefore of critical importance in successful hemostasis. One of the divalent cations released by …
B Gong, X Wei, J Qian, Y Lin - ACS Biomaterials Science & …, 2019 - ACS Publications
The cytoskeleton, a dynamic network of biopolymers with their associated cross-linking and motor proteins, is responsible for stabilizing cell shape and driving cell movement. This …