[HTML][HTML] Roles of Transepithelial Electrical Resistance in Mechanisms of Retinal Pigment Epithelial Barrier and Retinal Disorders

M Wang, H Li, F Wang - Discovery Medicine, 2022 - discoverymedicine.com
Transepithelial/transendothelial electrical resistance (TEER) is a widely accepted
quantitative technique to measure the integrity of tight junction dynamics in cell culture …

Human NGF “Painless” Ocular Delivery for Retinitis Pigmentosa: An In Vivo Study

D Napoli, N Orsini, G Salamone, MA Calvello… - Eneuro, 2024 - eneuro.org
Retinitis pigmentosa (RP) is a family of genetically heterogeneous diseases still without a
cure. Despite the causative genetic mutation typically not expressed in cone photoreceptors …

Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model

Y Xue, Y Zhou, CL Cepko - Elife, 2024 - elifesciences.org
Retinitis pigmentosa (RP) is an inherited retinal disease in which there is a loss of cone-
mediated daylight vision. As there are> 100 disease genes, our goal is to preserve cone …

Decitabine improves MMS-induced retinal photoreceptor cell damage by targeting DNMT3A and DNMT3B

Y Ji, M Zhao, X Qiao, GH Peng - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
Introduction Retinitis pigmentosa (RP) is a group of neurodegenerative retinopathies
causing blindness due to progressive and irreversible photoreceptor cell death. The …

[HTML][HTML] Curcumin as a Perspective Protection for Retinal Pigment Epithelium during Autophagy Inhibition in the Course of Retinal Degeneration

R Pinelli, M Ferrucci, F Biagioni, V Bumah… - Current …, 2023 - ncbi.nlm.nih.gov
Defective autophagy in the retinal pigment epithelium (RPE) is involved in retinal
degeneration, mostly in the course of age-related macular degeneration (AMD), which is an …

Use of machine learning for quantification of retinal pigment epithelium tight junctions improves assay sensitivity

MA Bray, Y Gao, M Twarog, YY Xu, N Buchanan… - bioRxiv, 2024 - biorxiv.org
The retinal pigment epithelium (RPE) is critical for maintaining outer retinal barrier
homeostasis. In age-related macular degeneration (AMD), the RPE can undergo a …