Exon identity crisis: disease-causing mutations that disrupt the splicing code
T Sterne-Weiler, JR Sanford - Genome biology, 2014 - Springer
Cis-acting RNA elements control the accurate expression of human multi-exon protein
coding genes. Single nucleotide variants altering the fidelity of this regulatory code and …
coding genes. Single nucleotide variants altering the fidelity of this regulatory code and …
Deciphering the plant splicing code: experimental and computational approaches for predicting alternative splicing and splicing regulatory elements
Extensive alternative splicing (AS) of precursor mRNAs (pre-mRNAs) in multicellular
eukaryotes increases the protein-coding capacity of a genome and allows novel ways to …
eukaryotes increases the protein-coding capacity of a genome and allows novel ways to …
Global dissection of alternative splicing in paleopolyploid soybean
Alternative splicing (AS) is common in higher eukaryotes and plays an important role in
gene posttranscriptional regulation. It has been suggested that AS varies dramatically …
gene posttranscriptional regulation. It has been suggested that AS varies dramatically …
Comprehensive analysis of alternative splicing in rice and comparative analyses with Arabidopsis
Background Recently, genomic sequencing efforts were finished for Oryza sativa (cultivated
rice) and Arabidopsis thaliana (Arabidopsis). Additionally, these two plant species have …
rice) and Arabidopsis thaliana (Arabidopsis). Additionally, these two plant species have …
A general definition and nomenclature for alternative splicing events
Understanding the molecular mechanisms responsible for the regulation of the
transcriptome present in eukaryotic cells is one of the most challenging tasks in the …
transcriptome present in eukaryotic cells is one of the most challenging tasks in the …
Alternative splicing in seasonal plasticity and the potential for adaptation to environmental change
Seasonal plasticity is accomplished via tightly regulated developmental cascades that
translate environmental cues into trait changes. Little is known about how alternative …
translate environmental cues into trait changes. Little is known about how alternative …
RNA-seq analysis reveals alternative splicing under salt stress in cotton, Gossypium davidsonii
G Zhu, W Li, F Zhang, W Guo - BMC genomics, 2018 - Springer
Background Numerous studies have focused on the regulation of gene expression in
response to salt stress at the transcriptional level; however, little is known about this process …
response to salt stress at the transcriptional level; however, little is known about this process …
Alternative splicing of RNA triplets is often regulated and accelerates proteome evolution
RK Bradley, J Merkin, NJ Lambert, CB Burge - PLoS biology, 2012 - journals.plos.org
Thousands of human genes contain introns ending in NAGNAG (N any nucleotide), where
both NAGs can function as 3′ splice sites, yielding isoforms that differ by …
both NAGs can function as 3′ splice sites, yielding isoforms that differ by …
The emergence of alternative 3′ and 5′ splice site exons from constitutive exons
E Koren, G Lev-Maor, G Ast - PLoS computational biology, 2007 - journals.plos.org
Alternative 3′ and 5′ splice site (ss) events constitute a significant part of all alternative
splicing events. These events were also found to be related to several aberrant splicing …
splicing events. These events were also found to be related to several aberrant splicing …
A computational approach for genome-wide mapping of splicing factor binding sites
Alternative splicing is regulated by splicing factors that serve as positive or negative
effectors, interacting with regulatory elements along exons and introns. Here we present a …
effectors, interacting with regulatory elements along exons and introns. Here we present a …