Cancer involves cells' abnormal growth and ability to invade or metastasize to different body
parts. Cancerous cells can divide uncontrollably and spread to other areas through the …

Maternal immune activation (MIA) is mediated by activation of inflammatory pathways
resulting in increased levels of cytokines and chemokines that cross the placental and blood …

Objective Immune system dysfunction is hypothesised to contribute to structural brain
changes through aberrant synaptic pruning in schizophrenia. However, evidence is mixed …

Over a decade of schizophrenia research using human induced pluripotent stem cell (iPSC)-
derived neural models has provided substantial data describing neurobiological …

Autism spectrum disorder (ASD) is a neurological disorder that manifests during early
development, impacting individuals through their ways of communicating, social behaviors …

Here we ask: What is productive signaling? How to define it, how to measure it, and most of
all, what are the parameters that determine it? Further, what determines the strength of …

The IFN‐γ/STAT1 immune signaling pathway impacts many homeostatic and pathological
aspects of neurons, beyond its canonical role in controlling intracellular pathogens. Well …

Maternal immune activation (MIA) during critical windows of gestation is correlated with long-
term neurodevelopmental deficits in the offspring, including increased risk for autism …

Animal models are useful preclinical tools for studying the pathogenesis of mental disorders
and the effectiveness of their treatment. While it is not possible to mimic all symptoms …

Rubella virus is an important human pathogen that can cause neurological deficits in a
developing fetus when contracted during pregnancy. Despite successful vaccination …