Microtubules in cell migration
C Garcin, A Straube - Essays in biochemistry, 2019 - portlandpress.com
Directed cell migration is critical for embryogenesis and organ development, wound healing
and the immune response. Microtubules are dynamic polymers that control directional …
and the immune response. Microtubules are dynamic polymers that control directional …
Affinity and specificity of motif-based protein–protein interactions
Y Ivarsson, P Jemth - Current opinion in structural biology, 2019 - Elsevier
It is becoming increasingly clear that eukaryotic cell physiology is largely controlled by
protein–protein interactions involving disordered protein regions, which usually interact with …
protein–protein interactions involving disordered protein regions, which usually interact with …
Multivalency ensures persistence of a+ TIP body at specialized microtubule ends
Microtubule plus-end tracking proteins (+ TIPs) control microtubule specialization and are as
such essential for cell division and morphogenesis. Here we investigated interactions and …
such essential for cell division and morphogenesis. Here we investigated interactions and …
Local control of intracellular microtubule dynamics by EB1 photodissociation
End-binding proteins (EBs) are adaptors that recruit functionally diverse microtubule plus-
end-tracking proteins (+ TIPs) to growing microtubule plus ends. To test with high spatial and …
end-tracking proteins (+ TIPs) to growing microtubule plus ends. To test with high spatial and …
MAPping tubulin mutations
TD Cushion, I Leca, DA Keays - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Microtubules are filamentous structures that play a critical role in a diverse array of cellular
functions including, mitosis, nuclear translocation, trafficking of organelles and cell shape …
functions including, mitosis, nuclear translocation, trafficking of organelles and cell shape …
Synergistic stabilization of microtubules by BUB-1, HCP-1, and CLS-2 controls microtubule pausing and meiotic spindle assembly
During cell division, chromosome segregation is orchestrated by a microtubule-based
spindle. Interaction between spindle microtubules and kinetochores is central to the bi …
spindle. Interaction between spindle microtubules and kinetochores is central to the bi …
[HTML][HTML] EB1 directly regulates APC-mediated actin nucleation
EB1 was discovered 25 years ago as a binding partner of the tumor suppressor
adenomatous polyposis coli (APC)[1]; however, the significance of EB1-APC interactions …
adenomatous polyposis coli (APC)[1]; however, the significance of EB1-APC interactions …
Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex
Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They
play important roles in neurons, as suggested by inhibition of axon growth and regeneration …
play important roles in neurons, as suggested by inhibition of axon growth and regeneration …
Phase separation of a microtubule plus-end tracking protein into a fluid fractal network
Microtubule plus-end tracking proteins (+ TIPs) participate in nearly all microtubule-based
cellular processes and have recently been proposed to function as liquid condensates …
cellular processes and have recently been proposed to function as liquid condensates …
rec-YnH enables simultaneous many-by-many detection of direct protein–protein and protein–RNA interactions
JS Yang, M Garriga-Canut, N Link, C Carolis… - Nature …, 2018 - nature.com
Knowing which proteins and RNAs directly interact is essential for understanding cellular
mechanisms. Unfortunately, discovering such interactions is costly and often unreliable. To …
mechanisms. Unfortunately, discovering such interactions is costly and often unreliable. To …