The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …

Background: Calcific aortic stenosis (CAS) is the most common valvular heart disease in
older adults and has no effective preventive therapies. Genome-wide association studies …

Trans-ethnic meta-analysis of genome-wide association studies (GWAS) across diverse
populations can increase power to detect complex trait loci when the underlying causal …

The past decade has seen a technological revolution in human genetics that has
empowered population-level investigations into genetic associations with phenotypes …

Genome-wide association studies have revolutionized our understanding of the genetic
underpinnings of cardiometabolic disease. Yet, the inadequate representation of individuals …

BACKGROUND: Individuals with type 2 diabetes (T2D) have an increased risk of coronary
artery disease (CAD), but questions remain about the underlying pathology. Identifying …

The limited literature and increasing interest in studies on cardiac electrophysiology,
explicitly focusing on cardiac ion channelopathies and sudden cardiac death in diverse …

QT interval prolongation is a heritable risk factor for ventricular arrhythmias and can
predispose to sudden death. Most genome-wide association studies (GWAS) of QT were …

C-reactive protein (CRP) is a circulating biomarker indicative of systemic inflammation. We
aimed to evaluate genetic associations with CRP levels among non-European-ancestry …

Contemporary studies have identified rs10494366 in the nitric oxide synthase 1 adaptor
protein (NOS1AP) gene as a new genetic marker in modulating the QT interval and sudden …