Breast cancer tumor microenvironment affects Treg/IL-17-producing Treg/Th17 cell axis: Molecular and therapeutic perspectives

F Seif, Z Torki, H Zalpoor, M Habibi… - Molecular Therapy …, 2023 - cell.com
The tumor microenvironment (TME) comprises a variety of immune cells, among which T
cells exert a prominent axial role in tumor development or anti-tumor responses in patients …

Crosstalk between miRNAs and DNA Methylation in Cancer

M Saviana, P Le, L Micalo, D Del Valle-Morales… - Genes, 2023 - mdpi.com
miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …

MicroRNAs; their therapeutic and biomarker properties

S Azizi Dargahlou, M Iriti, M Pouresmaeil… - Cellular, Molecular …, 2023 - cmbr-journal.com
MicroRNAs (miRNAs) are, small (roughly 19–25 nucleotides in length), conserved, non-
coding, single-stranded, and functional RNA molecules with the properties of gene …

MicroRNA-34 family in cancers: role, mechanism, and therapeutic potential

J Fu, S Imani, MY Wu, RC Wu - Cancers, 2023 - mdpi.com
Simple Summary The dysregulation of the miR-34 family has been shown to play an
important role in tumorigenesis and cancer progression. In this review, we summarized the …

Therapeutic delivery of tumor suppressor miRNAs for breast cancer treatment

SS Shinde, S Ahmed, JA Malik, U Hani, A Khanam… - Biology, 2023 - mdpi.com
Simple Summary The most frequent cancer in women is breast cancer (BC), which presents
a significant risk to their good health. Over the past few decades, several factors have …

Forging new therapeutic targets: efforts of tumor derived exosomes to prepare the pre-metastatic niche for cancer cell dissemination and dormancy

R Bhatia, J Chang, JL Munoz, ND Walker - Biomedicines, 2023 - mdpi.com
Tumor-derived exosomes play a multifaceted role in preparing the pre-metastatic niche,
promoting cancer dissemination, and regulating cancer cell dormancy. A brief review of …

Recent advances in novel miRNA mediated approaches for targeting breast cancer

SM Ahmadi, S Amirkhanloo… - Journal of Drug …, 2023 - Taylor & Francis
Breast cancer (BC) is considered one of the most frequent cancers among woman
worldwide. While conventional therapy has been successful in treating many cases of breast …

Exploring the potential role of circulating microRNAs as biomarkers for predicting clinical response to neoadjuvant therapy in breast cancer

LM Ruiz-Manriquez, C Villarreal-Garza… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC) is a leading cause of cancer-related deaths among women worldwide.
Neoadjuvant therapy (NAT) is increasingly being used to reduce tumor burden prior to …

Urinary miRNAs as a diagnostic tool for bladder cancer: a systematic review

AM Grimaldi, C Lapucci, M Salvatore, M Incoronato… - Biomedicines, 2022 - mdpi.com
Bladder cancer is the 10th most common cancer type worldwide. Cystoscopy represents the
gold standard for bladder cancer diagnosis, but this procedure is invasive and painful …

The role of MicroRNAs in HER2-Positive breast Cancer: where we are and future prospective

V Fogazzi, M Kapahnke, A Cataldo, I Plantamura… - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is the most diagnosed malignancy in woman worldwide
and, despite the availability of new innovative therapies, it remains the first cause of death …