Prevalence and burden of Toxoplasma gondii infection in HIV-infected people: a systematic review and meta-analysis

ZD Wang, SC Wang, HH Liu, HY Ma, ZY Li, F Wei… - The Lancet …, 2017 - thelancet.com
Background Worldwide, 30% of the world's population have antibodies to the intracellular
protozoan parasite Toxoplasma gondii and about 36· 7 million people are infected with HIV …

Toxoplasmosis in HIV infection: An overview

A Basavaraju - Tropical parasitology, 2016 - journals.lww.com
Toxoplasma gondii is an obligate intracellular protozoan parasite presenting as a zoonotic
infection distributed worldwide. In HIV-positive individuals, it causes severe opportunistic …

Synthesis and evaluation of novel arctigenin derivatives as potential anti-Toxoplasma gondii agents

H Zhang, QK Shen, H Wang, C Jin, CM Jin… - European Journal of …, 2018 - Elsevier
Four new series of arctigenin derivatives were designed, synthesised, and evaluated for
their anti-Toxoplasma gondii activity in vitro and in vivo. Among the synthesised compounds …

Global lysine crotonylation and 2-hydroxyisobutyrylation in phenotypically different Toxoplasma gondii parasites

D Yin, N Jiang, Y Zhang, D Wang, X Sang… - Molecular & cellular …, 2019 - ASBMB
Toxoplasma gondii is a unicellular protozoan parasite of the phylum Apicomplexa. The
parasite repeatedly goes through a cycle of invasion, division and induction of host cell …

Human Toxoplasma gondii infection in Nigeria: a systematic review and meta-analysis of data published between 1960 and 2019

SN Karshima, MN Karshima - BMC public health, 2020 - Springer
Background Over 70% of the worlds' population is infected by Toxoplasma gondii; a
pathogen capable of causing cerebral toxoplasmosis in HIV patients and neonatal …

Risk factors associated with seropositivity for Toxoplasma gondii in population-based studies among immunocompromised patients (pregnant women, HIV patients …

PO Odeniran, KF Omolabi, IO Ademola - Acta Tropica, 2020 - Elsevier
Toxoplasmosis in immunocompromised individuals can be life threatening. The information
needed for proper control and management strategies in endemic West African countries is …

In vitro activity of the interaction between taxifolin (dihydroquercetin) and pyrimethamine against Toxoplasma gondii

DA Abugri, WH Witola, AE Russell… - Chemical Biology & …, 2018 - Wiley Online Library
Toxoplasmosis is one of the most neglected zoonotic foodborne parasitic diseases that
cause public health and socioeconomic concern worldwide. The current drugs used for the …

Opportunistic parasitoses among Egyptian hemodialysis patients in relation to CD4+ T-cell counts: a comparative study

AI Shehata, F Hassanein, R Abdul-Ghani - BMC infectious diseases, 2019 - Springer
Background Some reports are available on the prevalence of opportunistic parasitoses
among hemodialysis (HD) patients, yet there is a paucity of data on the association of CD4+ …

Synthesis and evaluation of mycophenolic acid derivatives as potential anti-Toxoplasma gondii agents

FF Shang, MY Wang, JP Ai, QK Shen, HY Guo… - Medicinal Chemistry …, 2021 - Springer
Nineteen mycophenolic acid (MPA) derivatives were designed and synthesized, and their
anti-Toxoplasma activity evaluated for the first time. Among them, N-propylimidazole …

Synthesis, in vitro and in vivo biological evaluation of dihydroartemisinin derivatives with potential anti-Toxoplasma gondii agents

H Deng, X Huang, C Jin, CM Jin, ZS Quan - Bioorganic Chemistry, 2020 - Elsevier
In this study, four series of dihydroartemisinin derivatives were designed, synthesized, and
evaluated for anti-toxoplasma gondii activity, and calculated the selectivity index (SI). It was …