Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases

MR Mahmud, S Akter, SK Tamanna, L Mazumder… - Gut …, 2022 - Taylor & Francis
The human intestine hosts diverse microbial communities that play a significant role in
maintaining gut-skin homeostasis. When the relationship between gut microbiome and the …

The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain

ME Salliss, LV Farland, ND Mahnert… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Endometriosis is a chronic, burdensome condition that is historically
understudied. Consequently, there is a lack of understanding of the etiology of the disease …

The skin microbiome and the gut-skin axis

S Sinha, G Lin, K Ferenczi - Clinics in dermatology, 2021 - Elsevier
The microbiome plays a significant role in human health, homeostasis, immune system, and
disease pathogenesis. Disrupted communication between the microbiome and host has …

Multitarget approaches against multiresistant superbugs

DA Gray, M Wenzel - ACS Infectious Diseases, 2020 - ACS Publications
Despite efforts to develop new antibiotics, antibacterial resistance still develops too fast for
drug discovery to keep pace. Often, resistance against a new drug develops even before it …

Potential anti-COVID-19 therapeutics that block the early stage of the viral life cycle: structures, mechanisms, and clinical trials

RA Al-Horani, S Kar, KF Aliter - International Journal of Molecular …, 2020 - mdpi.com
The ongoing pandemic of coronavirus disease-2019 (COVID-19) is being caused by severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The disease continues to present …

Hidradenitis suppurativa: current and emerging treatments

SR Goldburg, BE Strober, MJ Payette - Journal of the American Academy …, 2020 - Elsevier
The treatment of hidradenitis suppurativa (HS) has remained challenging because of the
many knowledge gaps regarding etiology. However, recent studies into the pathogenesis of …

The interplay between gut microbiota and Parkinson's disease: Implications on diagnosis and treatment

A Varesi, LIM Campagnoli, F Fahmideh… - International journal of …, 2022 - mdpi.com
The bidirectional interaction between the gut microbiota (GM) and the Central Nervous
System, the so-called gut microbiota brain axis (GMBA), deeply affects brain function and …

Mitigative effects of topical Norfloxacin on an Imiquimod-induced murine model of psoriasis

H Ridha-Salman, EM Shihab, HK Hasan… - ACS Pharmacology & …, 2024 - ACS Publications
Psoriasis is a chronic, inflammatory dermatosis characterized by thickened, reddened, and
scaly skin lesions. Norfloxacin is a fluoroquinolone antibiotic with enhanced antioxidant, anti …

Antibiotic resistance in acne: changes, consequences and concerns

AS Karadag, M Aslan Kayıran, CY Wu… - Journal of the …, 2021 - Wiley Online Library
Antibiotic resistance in acne was first observed in the 1970s and has been a major concern
in dermatology since the 1980s. The resistance rates and types of antimicrobials have …

New avenues for Parkinson's disease therapeutics: disease-modifying strategies based on the gut microbiota

M Lorente-Picón, A Laguna - Biomolecules, 2021 - mdpi.com
Parkinson's disease (PD) is a multifactorial neurodegenerative disorder that currently affects
1% of the population over the age of 60 years, and for which no disease-modifying …