Mixed connective tissue disease: an overview of clinical manifestations, diagnosis and treatment

OD Ortega-Hernandez, Y Shoenfeld - Best Practice & Research Clinical …, 2012 - Elsevier
The most common clinical manifestations of mixed connective disease are Raynaud's
phenomenon, arthralgias, swollen joints, esophageal dysfunction, muscle weakness and …

Comparative assessment of vascular function in autoimmune rheumatic diseases: considerations of prevention and treatment

P Soltész, G Kerekes, H Dér, G Szücs, S Szántó… - Autoimmunity …, 2011 - Elsevier
Numerous autoimmune-inflammatory rheumatic diseases have been associated with
accelerated atherosclerosis or other types of vasculopathy leading to increased cardio-and …

Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling

L Taraseviciene-Stewart, MR Nicolls… - American journal of …, 2007 - atsjournals.org
Rationale: Severe pulmonary arterial hypertension (SPH) is a frequently lethal condition
characterized by pulmonary vascular remodeling and right heart strain or failure. SPH is also …

Clinical course, prognosis, and causes of death in mixed connective tissue disease

A Hajas, P Szodoray, B Nakken, J Gaal, E Zöld… - The Journal of …, 2013 - jrheum.org
Objective. To study the survival rate and prognostic indicators of mixed connective tissue
disease (MCTD) in a Hungarian population. Methods. Two hundred eighty patients with …

TH1/TH2 imbalance, measured by circulating and intracytoplasmic inflammatory cytokines–immunological alterations in acute coronary syndrome and stable coronary …

P Szodoray, O Timar, K Veres, H Der… - Scandinavian …, 2006 - Wiley Online Library
To describe how peripheral immune‐parameters reflect the inflammatory alterations of the
atherosclerotic plaques in coronary atherosclerosis. We measured general inflammatory …

Systemic lupus erythematosus, Sjögren syndrome, and mixed connective tissue disease in children and adolescents

SE Tarvin, KM O'Neil - Pediatric Clinics, 2018 - pediatric.theclinics.com
Systemic lupus erythematous (SLE), mixed connective tissue disease (MCTD), and Sjogren
syndrome (SS) are lifelong autoimmune diseases that present special challenges in the …

Distinct phenotypes in mixed connective tissue disease: subgroups and survival

P Szodoray, A Hajas, L Kardos, B Dezso, G Soos… - Lupus, 2012 - journals.sagepub.com
The aim of the present study was to assess the autoantibody profile, dominant clinical
symptoms and cluster characteristics of different Mixed connective tissue disease (MCTD …

Capillaroscopy is a dynamic process in mixed connective tissue disease

A de Holanda Mafaldo Diógenes, E Bonfá, R Fuller… - Lupus, 2007 - journals.sagepub.com
To determine the clinical relevance ofscleroderma-pattern'(SD-pattern) in mixed connective
tissue disease (MCTD), 63 (MCTD) patients (Kasukawa's criteria) were consecutively …

Immune pathogenesis of mixed connective tissue disease: a short analytical review

RW Hoffman, ME Maldonado - Clinical immunology, 2008 - Elsevier
Mixed Connective Tissue Disease (MCTD) was first described 35 years ago by Gordon C.
Sharp and his colleagues. In the ensuing decades, a clearer understanding of the clinical …

Vitamin D insufficiency in a large MCTD population

A Hajas, J Sandor, L Csathy, I Csipo, S Barath… - Autoimmunity …, 2011 - Elsevier
OBJECTIVES: The aim of the present study was to evaluate the vitamin D status in patients
with mixed connective tissue disease (MCTD) and to determine which clinical symptoms …