Mitochondria are vital organelles with distinct morphological features and functional
properties. The dynamic network of mitochondria undergoes structural and functional …

Mitochondria are key determinants of cellular health. However, the functional role of
mitochondria varies from cell to cell depending on the relative demands for energy …

Mitochondria are associated with various cellular activities critical to homeostasis,
particularly in the nervous system. The plastic architecture of the mitochondrial network and …

In the current model of mitochondrial trafficking, Miro1 and Miro2 Rho‐GTP ases regulate
mitochondrial transport along microtubules by linking mitochondria to kinesin and dynein …

Neurons, perhaps more than any other cell type, depend on mitochondrial trafficking for their
survival. Recent studies have elucidated a motor/adaptor complex on the mitochondrial …

Vigorous transport of cytoplasmic components along axons over substantial distances is
crucial for the maintenance of neuron structure and function. The transport of mitochondria …

Mitochondria are mobile organelles and cells regulate mitochondrial movement in order to
meet the changing energy needs of each cellular region. Ca 2+ signaling, which halts both …

Parkinson's disease (PD) is marked by the gradual degeneration of dopaminergic neurons
and the intracellular build-up of Lewy bodies rich in α-synuclein protein. This impairs various …

Organelle transport is vital for the development and maintenance of axons, in which the
distances between sites of organelle biogenesis, function, and recycling or degradation can …

To address questions about mechanisms of filament-based organelle transport, a system
was developed to image and track mitochondria in an intact Drosophila nervous system …