Translational relevance and recent advances of animal models of abdominal aortic aneurysm

J Sénémaud, G Caligiuri, H Etienne… - … , and vascular biology, 2017 - Am Heart Assoc
Human abdominal aortic aneurysm (AAA) pathophysiology is not yet completely understood.
In conductance arteries, the insoluble extracellular matrix, synthesized by vascular smooth …

Shear stress and aneurysms: a review

B Staarmann, M Smith, CJ Prestigiacomo - Neurosurgical focus, 2019 - thejns.org
Wall shear stress, the frictional force of blood flow tangential to an artery lumen, has been
demonstrated in multiple studies to influence aneurysm formation and risk of rupture. In this …

Enhancement of cerebrovascular 4D flow MRI velocity fields using machine learning and computational fluid dynamics simulation data

DR Rutkowski, A Roldán-Alzate, KM Johnson - Scientific reports, 2021 - nature.com
Blood flow metrics obtained with four-dimensional (4D) flow phase contrast (PC) magnetic
resonance imaging (MRI) can be of great value in clinical and experimental cerebrovascular …

Small intracranial aneurysms: diagnostic accuracy of CT angiography

ZL Yang, QQ Ni, UJ Schoepf, CN De Cecco, H Lin… - Radiology, 2017 - pubs.rsna.org
Purpose To assess the accuracy of computed tomographic (CT) angiography for diagnosis
of cerebral aneurysms 5 mm or smaller, with digital subtraction angiography (DSA) as the …

Prediction of cerebral aneurysm hemodynamics with porous-medium models of flow-diverting stents via deep learning

G Li, X Song, H Wang, S Liu, J Ji, Y Guo, A Qiao… - Frontiers in …, 2021 - frontiersin.org
The interventional treatment of cerebral aneurysm requires hemodynamics to provide proper
guidance. Computational fluid dynamics (CFD) is gradually used in calculating cerebral …

Substrate stiffness influences structural and functional remodeling in induced pluripotent stem cell-derived cardiomyocytes

A Körner, M Mosqueira, M Hecker… - Frontiers in Physiology, 2021 - frontiersin.org
Novel treatment strategies for cardiac tissue regeneration are heading for the use of
engineered cardiac tissue made from induced pluripotent stem cell-derived cardiomyocytes …

Risk factors and predictive indicators of rupture in cerebral aneurysms

X Wang, X Huang - Frontiers in Physiology, 2024 - frontiersin.org
Cerebral aneurysms are abnormal dilations of blood vessels in the brain that have the
potential to rupture, leading to subarachnoid hemorrhage and other serious complications …

4D-flow MRI: technique and applications

A Sträter, A Huber, J Rudolph, M Berndt… - RöFo-Fortschritte auf …, 2018 - thieme-connect.com
Hintergrund Der Blutfluss durch das Herz und die großen Gefäße erfolgt pulsatil und
unterliegt zeitlichen wie auch multidirektionalen Schwankungen. Bisher ist die Erfassung …

Effects of low and high aneurysmal wall shear stress on endothelial cell behavior: differences and similarities

S Morel, S Schilling, MR Diagbouga… - Frontiers in …, 2021 - frontiersin.org
Background: Intracranial aneurysms (IAs) result from abnormal enlargement of the arterial
lumen. IAs are mostly quiescent and asymptomatic, but their rupture leads to severe brain …

Relationship of A1 segment hypoplasia to anterior communicating artery aneurysm morphology and risk factors for aneurysm formation

L Rinaldo, BA McCutcheon, ME Murphy, M Bydon… - Journal of …, 2016 - thejns.org
OBJECTIVE Hypoplasia of the A 1 segment of the anterior cerebral artery is frequently
observed in patients with anterior communicating artery (ACoA) aneurysms. The effect of this …