The use of hadron beams, especially proton beams, in cancer radiotherapy has expanded
rapidly in the past two decades. To fully realize the advantages of hadron therapy over …

Purpose: While Monte Carlo particle transport has proven useful in many areas (treatment
head design, dose calculation, shielding design, and imaging studies) and has been …

Intensity modulated proton therapy (IMPT) implies the electromagnetic spatial control of well-
circumscribed “pencil beams” of protons of variable energy and intensity. Proton pencil …

We present a full-scale clinical prototype system for in vivo range verification of proton pencil-
beams using the prompt gamma-ray spectroscopy method. The detection system consists of …

PURPOSE: To quantify the impact of respiratory motion on the treatment of lung tumors with
spot scanning proton therapy. METHODS AND MATERIALS: Four-dimensional Monte Carlo …

Reliable treatment planning of highly conformal scanned ion beam therapy demands
accurate tools for the determination and characterization of the individual pencil-like beams …

The purpose of this work was to compare the clinical adaptation of prompt gamma (PG)
imaging and positron emission tomography (PET) as independent tools for non-invasive …

Relative motion between a tumor and a scanning proton beam results in a degradation of
the dose distribution (interplay effect). This study investigates the relationship between beam …

Purpose Setup, range, and anatomical uncertainties influence the dose delivered with
intensity modulated proton therapy (IMPT), but clinical quantification of these errors for …

Background Accurate and efficient dose calculation is essential for on‐line adaptive
planning in proton therapy. Deep learning (DL) has shown promising dose prediction results …