[HTML][HTML] Management of elderly patients with NSCLC; updated expert's opinion paper: EORTC Elderly Task Force, Lung Cancer Group and International Society for …

AG Pallis, C Gridelli, U Wedding, C Faivre-Finn… - Annals of oncology, 2014 - Elsevier
Non-small-cell lung cancer (NSCLC) is a very common disease in the elderly population
and its incidence in this particular population is expected to increase further, because of the …

Epidemiology and management of common pulmonary diseases in older persons

KM Akgün, K Crothers, M Pisani - Journals of Gerontology …, 2012 - academic.oup.com
Pulmonary disease prevalence increases with age and contributes to morbidity and mortality
in older patients. Dyspnea in older patients is often ascribed to multiple etiologies such as …

Disruption of STAT3 by niclosamide reverses radioresistance of human lung cancer

S You, R Li, D Park, M Xie, GL Sica, Y Cao… - Molecular cancer …, 2014 - AACR
A major challenge affecting the outcomes of patients with lung cancer is the development of
acquired radioresistance. However, the mechanisms underlying the development of …

[HTML][HTML] Discovery of small molecule Bak activator for lung cancer therapy

D Park, ASM Anisuzzaman, AT Magis, G Chen… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Bak is a major proapoptotic Bcl2 family member and a required molecule for
apoptotic cell death. High levels of endogenous Bak were observed in both small cell lung …

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer

D Park, AT Magis, R Li, TK Owonikoko, GL Sica… - Cancer research, 2013 - AACR
Bcl-XL is a major antiapoptotic protein in the Bcl-2 family whose overexpression is more
widely observed in human lung cancer cells than that of Bcl-2, suggesting that Bcl-XL is …

[HTML][HTML] Updated survival and outcomes for older adults with inoperable stage III non-small-cell lung cancer treated with cisplatin, etoposide, and concurrent chest …

SI Jalal, HD Riggs, A Melnyk, D Richards, A Agarwala… - Annals of oncology, 2012 - Elsevier
Background Concurrent chemoradiation with etoposide and cisplatin (EP/XRT) is standard
treatment for inoperable stage III locally advanced non-small-cell lung cancer (LA-NSCLC) …

[HTML][HTML] Progress in standard of care therapy and modest survival benefits in the treatment of non-small cell lung cancer patients in the Netherlands in the last 20 years

MA Van der Drift, HE Karim-Kos, S Siesling… - Journal of thoracic …, 2012 - Elsevier
Introduction: Lung cancer is the leading cause of cancer mortality worldwide. We analyzed
changes in treatment and their potential effect on survival of non-small cell lung cancer …

Early and long-term results of pulmonary resection for non-small-cell lung cancer in patients over 75 years of age: a multi-institutional study

A Dell'Amore, M Monteverde, N Martucci… - … and thoracic surgery, 2013 - academic.oup.com
OBJECTIVES Older lung cancer patients with multiple morbidities are increasingly referred
to thoracic surgery departments. The aim of this multicenter study was to analyse the …

[HTML][HTML] Prognostic factors in stage III non-small-cell lung cancer patients

SE Urvay, B Yucel, E Erdis, N Turan - Asian Pacific journal of …, 2016 - ncbi.nlm.nih.gov
Aim: The objective of this study is to investigate prognostic factors affecting survival of
patients undergoing concurrent or sequential chemoradiotherapy (CRT) for stage III non …

Persisting gaps in optimal care of stage III non-small cell lung cancer: an Australian patterns of care analysis

K Woodford, K Koo, J Reynolds, RG Stirling… - The …, 2023 - academic.oup.com
Background Wide variation exists globally in the treatment and outcomes of stage III patients
with non–small cell lung cancer (NSCLC). We conducted an up-to-date patterns of care …