Polymer fiber scaffolds for bone and cartilage tissue engineering

Y Zhang, X Liu, L Zeng, J Zhang, J Zuo… - Advanced Functional …, 2019 - Wiley Online Library
Successful regeneration of weight‐bearing bone defects and critical‐sized cartilage defects
remains a major challenge in clinical orthopedics. In the past decades, biodegradable …

Electrospinning of polymer nanofibers for tissue regeneration

T Jiang, EJ Carbone, KWH Lo, CT Laurencin - Progress in polymer …, 2015 - Elsevier
Repair and regeneration of human tissues and organs using biomaterials, cells, and/or
growth factors is a great challenge for tissue engineers and surgeons. The convergence of …

Fabrication and properties of polycaprolactone composites containing calcium phosphate-based ceramics and bioactive glasses in bone tissue engineering: a review

F Hajiali, S Tajbakhsh, A Shojaei - Polymer reviews, 2018 - Taylor & Francis
Polycaprolactone (PCL) is a bioresorbable and biocompatible polymer that has been widely
used in long-term implants and controlled drug release applications. However, when it …

Recent advances in electrospun polycaprolactone based scaffolds for wound healing and skin bioengineering applications

B Joseph, R Augustine, N Kalarikkal, S Thomas… - Materials Today …, 2019 - Elsevier
Abstract Electrospun poly (ƹ-caprolactone)(PCL) scaffolds incorporated with bioactive
materials play a key role in tissue engineering applications due to their extra cellular matrix …

Bio-inspired in situ crosslinking and mineralization of electrospun collagen scaffolds for bone tissue engineering

C Dhand, ST Ong, N Dwivedi, SM Diaz, JR Venugopal… - Biomaterials, 2016 - Elsevier
Bone disorders are the most common cause of severe long term pain and physical disability,
and affect millions of people around the world. In the present study, we report bio-inspired …

Electrospun polycaprolactone nanofibers as a potential oromucosal delivery system for poorly water-soluble drugs

T Potrč, S Baumgartner, R Roškar, O Planinšek… - European Journal of …, 2015 - Elsevier
The number of poorly water-soluble drug candidates is rapidly increasing; this represents a
major challenge for the pharmaceutical industry. As a consequence, novel formulation …

Preparation and characterization of polycaprolactone/chitosan-g-polycaprolactone/hydroxyapatite electrospun nanocomposite scaffolds for bone tissue engineering

IS Sani, M Rezaei, AB Khoshfetrat… - International Journal of …, 2021 - Elsevier
Chitosan (CS) and poly (ε-caprolactone)(PCL) are two most usable polymers in biomedical
applications. In this study, chitosan has been modified and incorporated with poly (ε …

Composite PCL/HA/simvastatin electrospun nanofiber coating on biodegradable Mg alloy for orthopedic implant application

AI Rezk, HM Mousa, J Lee, CH Park, CS Kim - Journal of Coatings …, 2019 - Springer
Recently, magnesium (Mg) and its alloys have attracted more attention because of their
biodegradability and fascinating mechanical properties in the medical field. However, their …

Osteoinductive fibrous scaffolds of biopolymer/mesoporous bioactive glass nanocarriers with excellent bioactivity and long-term delivery of osteogenic drug

A El-Fiqi, JH Kim, HW Kim - ACS applied materials & interfaces, 2015 - ACS Publications
Designing scaffolds with bioactive composition and long-term drug delivery capacity is a
promising method to improve the therapeutic efficacy in bone regeneration. Herein …

In situ generation of cellulose nanocrystals in polycaprolactone nanofibers: effects on crystallinity, mechanical strength, biocompatibility, and biomimetic mineralization

MK Joshi, AP Tiwari, HR Pant… - … applied materials & …, 2015 - ACS Publications
Post-electrospinning treatment is a facile process to improve the properties of electrospun
nanofibers for various applications. This technique is commonly used when direct …