CD4 T helper cell subsets and related human immunological disorders

X Zhu, J Zhu - International journal of molecular sciences, 2020 - mdpi.com
The immune system plays a critical role in protecting hosts from the invasion of organisms.
CD4 T cells, as a key component of the immune system, are central in orchestrating adaptive …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

The multifaceted roles of macrophages in bone regeneration: a story of polarization, activation and time

C Schlundt, H Fischer, CH Bucher, C Rendenbach… - Acta biomaterialia, 2021 - Elsevier
To present knowledge, macrophages are found in all tissues of the human body. They are a
cell population with high plasticity which come with a multitude of functions which appear to …

The era of cytotoxic CD4 T cells

M Cenerenti, M Saillard, P Romero… - Frontiers in …, 2022 - frontiersin.org
In 1986, Mosmann and Coffman identified 2 functionally distinct subsets of activated CD4 T
cells, Th1 and Th2 cells, being key in distinct T cell mediated responses. Over the past three …

Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi, M Nader - Pharmacological Reviews, 2021 - Elsevier
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system

N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

IFITM proteins: Understanding their diverse roles in viral infection, cancer, and immunity

M Gómez-Herranz, J Taylor, RD Sloan - Journal of Biological Chemistry, 2023 - ASBMB
Interferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …

Trade-offs (and constraints) in organismal biology

T Garland Jr, CJ Downs… - … and biochemical zoology, 2022 - journals.uchicago.edu
Trade-offs and constraints are inherent to life, and studies of these phenomena play a
central role in both organismal and evolutionary biology. Trade-offs can be defined …

[HTML][HTML] Hepatitis E virus: Epidemiology, diagnosis, clinical manifestations, and treatment

AT Aslan, HY Balaban - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
The hepatitis E virus (HEV) is the fifth known form of viral hepatitis and was first recognized
as the cause of an epidemic of unexplained acute hepatitis in the early 1980s. Globally, it is …

Marine omega-3 fatty acids and inflammatory processes: Effects, mechanisms and clinical relevance

PC Calder - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2015 - Elsevier
Inflammation is a condition which contributes to a range of human diseases. It involves a
multitude of cell types, chemical mediators, and interactions. Eicosapentaenoic acid (EPA) …