The life and times of a tRNA
EM Phizicky, AK Hopper - RNA, 2023 - rnajournal.cshlp.org
The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …
and insights in the last several years. We now have unprecedented knowledge of each step …
RNA nucleotide methylation: 2021 update
Among RNA modifications, transfer of methylgroups from the typical cofactor S‐adenosyl‐l‐
methionine by methyltransferases (MTases) to RNA is by far the most common reaction …
methionine by methyltransferases (MTases) to RNA is by far the most common reaction …
Identification of direct targets and modified bases of RNA cytosine methyltransferases
V Khoddami, BR Cairns - Nature biotechnology, 2013 - nature.com
The extent and biological impact of RNA cytosine methylation are poorly understood, in part
owing to limitations of current techniques for determining the targets of RNA …
owing to limitations of current techniques for determining the targets of RNA …
Cytosine DNA Methylation Is Found in Drosophila melanogaster but Absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and Other Yeast Species
F Capuano, M Mülleder, R Kok, HJ Blom… - Analytical …, 2014 - ACS Publications
The methylation of cytosine to 5-methylcytosine (5-meC) is an important epigenetic DNA
modification in many bacteria, plants, and mammals, but its relevance for important model …
modification in many bacteria, plants, and mammals, but its relevance for important model …
Mechanism and biological role of Dnmt2 in nucleic acid methylation
A Jeltsch, A Ehrenhofer-Murray, TP Jurkowski… - RNA biology, 2017 - Taylor & Francis
ABSTRACT A group of homologous nucleic acid modification enzymes called Dnmt2,
Trdmt1, Pmt1, DnmA, and Ehmet in different model organisms catalyze the transfer of a …
Trdmt1, Pmt1, DnmA, and Ehmet in different model organisms catalyze the transfer of a …
Dnmt2-dependent methylomes lack defined DNA methylation patterns
G Raddatz, PM Guzzardo, N Olova… - Proceedings of the …, 2013 - National Acad Sciences
Several organisms have retained methyltransferase 2 (Dnmt2) as their only candidate DNA
methyltransferase gene. However, information about Dnmt2-dependent methylation patterns …
methyltransferase gene. However, information about Dnmt2-dependent methylation patterns …
The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis
The Dnmt2 enzyme utilizes the catalytic mechanism of eukaryotic DNA methyltransferases to
methylate several tRNA s at cytosine 38. Dnmt2 mutant mice, flies, and plants were reported …
methylate several tRNA s at cytosine 38. Dnmt2 mutant mice, flies, and plants were reported …
NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs
S Haag, AS Warda, J Kretschmer, MA Günnigmann… - Rna, 2015 - rnajournal.cshlp.org
Many cellular RNAs require modification of specific residues for their biogenesis, structure,
and function. 5-methylcytosine (m5C) is a common chemical modification in DNA and RNA …
and function. 5-methylcytosine (m5C) is a common chemical modification in DNA and RNA …
Transcriptome-wide mapping of RNA 5-methylcytosine in Arabidopsis mRNAs and noncoding RNAs
Posttranscriptional methylation of RNA cytosine residues to 5-methylcytosine (m5C) is an
important modification with diverse roles, such as regulating stress responses, stem cell …
important modification with diverse roles, such as regulating stress responses, stem cell …
tRNA-derived small RNAs: biogenesis, modification, function and potential impact on human disease development
V Oberbauer, MR Schaefer - Genes, 2018 - mdpi.com
Transfer RNAs (tRNAs) are abundant small non-coding RNAs that are crucially important for
decoding genetic information. Besides fulfilling canonical roles as adaptor molecules during …
decoding genetic information. Besides fulfilling canonical roles as adaptor molecules during …