Covert actions of growth hormone: fibrosis, cardiovascular diseases and cancer

JJ Kopchick, R Basu, DE Berryman… - Nature Reviews …, 2022 - nature.com
Since its discovery nearly a century ago, over 100,000 studies of growth hormone (GH) have
investigated its structure, how it interacts with the GH receptor and its multiple actions. These …

Musculoskeletal effects of altered GH action

JA Young, S Zhu, EO List, S Duran-Ortiz… - Frontiers in …, 2022 - frontiersin.org
Growth hormone (GH) is a peptide hormone that can signal directly through its receptor or
indirectly through insulin-like growth factor 1 (IGF-1) stimulation. GH draws its name from its …

Excess growth hormone alters the male mouse gut microbiome in an age-dependent manner

EA Jensen, JA Young, Z Jackson, J Busken… - …, 2022 - academic.oup.com
The gut microbiome has an important role in host development, metabolism, growth, and
aging. Recent research points toward potential crosstalk between the gut microbiota and the …

Growth Hormone Alters Circulating Levels of Glycine and Hydroxyproline in Mice

JA Young, S Duran-Ortiz, S Bell, K Funk, Y Tian, Q Liu… - Metabolites, 2023 - mdpi.com
Growth hormone (GH) has established effects on protein metabolism, such as increasing
protein synthesis and decreasing amino acid degradation, but its effects on circulating …

Acromegaly is associated with a distinct oral and gut microbiota

S Sahin, A Gundogdu, U Nalbantoglu, P Kadioglu… - Pituitary, 2022 - Springer
Purpose Our aim was to investigate the changes in the composition of oral and gut
microbiota in patients with newly diagnosed acromegaly and their relationship with IGF-1 …

Era of biotics in managing colonic disorders

S Bhatt, K Anitha, SK Sah, NP Apte… - Advanced Drug Delivery …, 2024 - Elsevier
Imbalance in gut microbiota is responsible for pathological progression of various colonic
disorders. These gut microbiota affects the immune system of the host as well as modifies …

Exploring Fibrosis in Bovine Growth Hormone (bGH) Transgenic Mice

Z Kington - 2023 - rave.ohiolink.edu
Fibrosis, a pathological process characterized by excess extracellular matrix (ECM)
deposition, can occur in many internal organs and tissues in response to various stimuli. As …

Colonoscopic evaluation of acromegalic patients: a single center experience

YE Günay, S Durak, AM Coşar, M Erkut… - Journal of Medicine and …, 2022 - dergipark.org.tr
Aim: To investigate the importance and necessity of colonoscopic screening in patients with
acromegaly. Methods: This study included 82 patients with acromegaly and, 82 healthy …