[HTML][HTML] Innovative Strategies in Drug Repurposing to Tackle Intracellular Bacterial Pathogens

B Lorente-Torres, J Llano-Verdeja, P Castañera… - Antibiotics, 2024 - mdpi.com
Intracellular bacterial pathogens pose significant public health challenges due to their ability
to evade immune defenses and conventional antibiotics. Drug repurposing has recently …

Challenges in Diagnosing Primary Tubercular Chorioretinitis and Ocular Tuberculosis in Resource-Limited Settings of Bangladesh

I Khalil - Indian Journal of Tuberculosis, 2024 - Elsevier
Tuberculosis is a pressing global health concern that affects not only the respiratory system
but also various extrapulmonary sites. In addition to pulmonary symptoms, tuberculosis can …

[HTML][HTML] Malnutrition and unsuccessful tuberculosis treatment among people with multi-drug resistant tuberculosis in Uganda: A retrospective analysis

S Engoru, F Bajunirwe, J Izudi - Journal of Clinical Tuberculosis and Other …, 2024 - Elsevier
Rationale Multi-drug-resistant tuberculosis (MDR-TB) poses a significant public health
challenge to the control and successful eradication of TB globally. Suboptimal treatment …

Drug resistance profiles of Mycobacterium tuberculosis clinical isolates by genotype MTBDRplus line probe assay in Zambia: findings and implications

MH Kangongwe, W Mwanza, M Mwamba… - JAC-Antimicrobial …, 2024 - academic.oup.com
Background The emergence of drug resistance is a threat to global tuberculosis (TB)
elimination goals. This study investigated the drug resistance profiles of Mycobacterium …

Analyzing nutrition risks and blood biomarkers in hospitalized patients with tuberculosis: Insights from a 2020 hospital‐based study

Z Li, P Wang, J Ma, Y Chen… - Nutrition in Clinical Practice, 2024 - Wiley Online Library
Background There exists a bidirectional relationship between tuberculosis (TB) and
nutrition, wherein they mutually influence and interact causally. However, current guidance …

Genetic insights into the connection between pulmonary TB and non-communicable diseases: An integrated analysis of shared genes and potential treatment targets

A Mahjabeen, MZ Hasan, MT Rahman, MA Islam… - Plos one, 2024 - journals.plos.org
Background Pulmonary Tuberculosis (PTB) is a significant global health issue due to its high
incidence, drug resistance, contagious nature, and impact on people with compromised …

[HTML][HTML] Nanomedicines for Pulmonary Drug Delivery: Overcoming Barriers in the Treatment of Respiratory Infections and Lung Cancer

R Fernández-García, AI Fraguas-Sánchez - Pharmaceutics, 2024 - pmc.ncbi.nlm.nih.gov
The pulmonary route for drug administration has garnered a great deal of attention in
therapeutics for treating respiratory disorders. It allows for the delivery of drugs directly to the …

Epidemiology and outcomes of patients with tuberculosis requiring extracorporeal membrane oxygenation: An ELSO registry analysis

AAIT Hssain, A Vahedian-Azimi, M Schmidt… - Intensive and Critical …, 2025 - Elsevier
Purpose This study aimed to analyze data from the Extracorporeal Life Support Organization
(ELSO) registry to elucidate the epidemiology and outcomes of patients with tuberculosis …

[HTML][HTML] Quality of Life Evaluation Before and After Pulmonary Lobe Resection for Benign Diseases: A Comparative Study Among Patients with Tuberculosis …

A Nicola, TM Porosnicu, SMD Laitin, C Oancea… - Diseases, 2024 - mdpi.com
Background: Pulmonary lobe resection is a common surgical intervention for various benign
lung diseases, including tuberculosis (TB), bronchiectasis, and benign lung nodules. While …

Characteristics, predictors and consequences of tuberculosis treatment interruption: A multicentre retrospective cohort study

AL Oh, M Makmor‐Bakry, F Islahudin… - Tropical Medicine & …, 2024 - Wiley Online Library
Objectives Treatment interruption is associated with poor tuberculosis (TB) treatment
outcomes and increased drug resistance. To address the issue, we aimed to investigate the …