Autonomous discovery in the chemical sciences part I: Progress
This two‐part Review examines how automation has contributed to different aspects of
discovery in the chemical sciences. In this first part, we describe a classification for …
discovery in the chemical sciences. In this first part, we describe a classification for …
Autonomous discovery in the chemical sciences part II: outlook
This two‐part Review examines how automation has contributed to different aspects of
discovery in the chemical sciences. In this second part, we reflect on a selection of …
discovery in the chemical sciences. In this second part, we reflect on a selection of …
[HTML][HTML] Neuroprotective potential of ellagic acid: a critical review
Ellagic acid (EA) is a dietary polyphenol present in various fruits, vegetables, herbs, and
nuts. It exists either independently or as part of complex structures, such as ellagitannins …
nuts. It exists either independently or as part of complex structures, such as ellagitannins …
In silico polypharmacology of natural products
Natural products with polypharmacological profiles have demonstrated promise as novel
therapeutics for various complex diseases, including cancer. Currently, many gaps exist in …
therapeutics for various complex diseases, including cancer. Currently, many gaps exist in …
Machine learning approaches for elucidating the biological effects of natural products
R Zhang, X Li, X Zhang, H Qin, W Xiao - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2000 to 2020 Machine learning (ML) is an efficient tool for the prediction of
bioactivity and the study of structure–activity relationships. Over the past decade, an …
bioactivity and the study of structure–activity relationships. Over the past decade, an …
Baicalein as a potent neuroprotective agent: A review
In recent times, neurodegenerative diseases are the most challenging global health
problems. Neuronal cell death or damage is a key factor for many neurodegenerative …
problems. Neuronal cell death or damage is a key factor for many neurodegenerative …
Therapeutic potential of oridonin and its analogs: from anticancer and antiinflammation to neuroprotection
Oridonin, a diterpenoid natural product commonly used in East Asian herbal medicine, is
garnering increased attention in the biomedical community due to its extensive biological …
garnering increased attention in the biomedical community due to its extensive biological …
Ferulic acid-mediated modulation of apoptotic signaling pathways in cancer
Abstract Ferulic acid (4-hydroxy-3-methoxycinnamic acid, FA), a hydroxycinnamic acid
derived from various seeds, nuts, leaves, and fruits, exists in a free form as well as is …
derived from various seeds, nuts, leaves, and fruits, exists in a free form as well as is …
Computational and in-vitro validation of natural molecules as potential acetylcholinesterase inhibitors and neuroprotective agents
A Kumar, V Mehta, U Raj, PK Varadwaj… - Current Alzheimer …, 2019 - ingentaconnect.com
Background: Cholinesterase inhibitors are the first line of therapy for the management of
Alzheimer's disease (AD), however, it is now established that they provide only temporary …
Alzheimer's disease (AD), however, it is now established that they provide only temporary …
Discovery of VEGFR2 inhibitors by integrating naïve Bayesian classification, molecular docking and drug screening approaches
D Kang, X Pang, W Lian, L Xu, J Wang, H Jia… - RSC …, 2018 - pubs.rsc.org
The high morbidity and mortality of cancer make it one of the leading causes of global death,
thus it is an urgent need to develop effective drugs for cancer therapy. Vascular endothelial …
thus it is an urgent need to develop effective drugs for cancer therapy. Vascular endothelial …