Genetic alterations drive tumor onset and progression. However, the cross-talk between
tumor cells and the benign components of the surrounding stroma can also promote the …

Engineering complex tissues and whole organs has the potential to dramatically impact
translational medicine in several avenues. Organ engineering is a discipline that integrates …

Accumulating evidence indicates that the physicochemical properties of biomaterials exert
profound influences on stem cell fate decisions. However, matrix-based regulation selected …

Tumors are composed of heterogeneous phenotypes, each having different sensitivities to
the microenvironment. One microenvironment characteristic–matrix stiffness–helps to …

Cytoadherence of Trichomonas vaginalis to human vaginal epithelial cells (h VECs) was
previously shown to involve surface lipoglycans and several reputed adhesins on the …

The classical Prandtl–Tomlinson model is the most famous and efficient method to describe
the stick–slip phenomenon and the resulting friction between a slider and a corrugated …

Exosomes are cell-secreted microvesicles that play important roles in epithelial ovarian
cancer (EOC) progression, as they are constantly secreted into ascites fluids. While cells …

The specialized pericellular matrix (PCM) surrounding chondrocytes within articular
cartilage is critical to the tissue's health and longevity. Growing evidence suggests that PCM …

Due to the heterogeneity of cancer cell populations, the traditional evaluation approach of
cell viability based on the cell counting assay is quite inaccurate for the dose–response test …

Mesenchymal cell migration is an integral process in development and healing. The process
is regulated by both mechanical and biochemical properties. Mechanical properties of the …