The control of body and organ growth is essential for the development of adults with proper
size and proportions, which is important for survival and reproduction. In animals, adult body …

In animals, developmental timing of sexual maturation is tightly linked to nutrition and
growth. Maturation only occurs once the juvenile has acquired sufficient nutrients and …

INTRODUCTION Animals have a remarkable capacity to maintain a constant size, even in
the face of genetic and environmental perturbations. Size imperfections and asymmetries …

An important unanswered question in regenerative biology is to what extent regeneration is
accomplished by the reactivation of gene regulatory networks used during development …

Adult size and fitness are controlled by a combination of genetics and environmental cues.
In Drosophila, growth is confined to the larval phase and final body size is impacted by the …

Steroid hormones trigger the onset of sexual maturation in animals by initiating genetic
response programs that are determined by steroid pulse frequency, amplitude and duration …

Mechanisms that coordinate growth during development are essential for producing animals
with proper organ proportion. Here we describe a pathway through which tissues …

Checkpoints arrest biological processes, allowing time for error correction. The
phenomenon of checkpoint override during cellular self-replication is biologically critical, but …

Background Drosophila is a powerful model for the study of factors modulating innate
immunity. This study examines the effect of water-loss dehydration on innate immune …

In Drosophila melanogaster, loss of regenerative capacity in wing imaginal discs coincides
with an increase in systemic levels of the steroid hormone ecdysone, a key coordinator of …