[HTML][HTML] Emerging diversity of channelrhodopsins and their structure-function relationships

EG Govorunova, OA Sineshchekov… - Frontiers in cellular …, 2022 - frontiersin.org
Cation and anion channelrhodopsins (CCRs and ACRs, respectively) from phototactic algae
have become widely used as genetically encoded molecular tools to control cell membrane …

Novel optogenetics tool: Gt_CCR4, a light-gated cation channel with high reactivity to weak light

S Hososhima, S Shigemura, H Kandori… - Biophysical Reviews, 2020 - Springer
Optogenetics is a growing technique which allows manipulation of biological events simply
by illumination. The technique is appreciated especially in the neuroscience field because of …

Bridge: A graph-based algorithm to analyze dynamic H-bond networks in membrane proteins

M Siemers, M Lazaratos, K Karathanou… - Journal of chemical …, 2019 - ACS Publications
Membrane proteins that function as transporters or receptors must communicate with both
sides of the lipid bilayer in which they sit. This long distance communication enables …

[HTML][HTML] A Chimera Na+-Pump Rhodopsin as an Effective Optogenetic Silencer

MR Hoque, T Ishizuka, K Inoue, R Abe-Yoshizumi… - PLoS …, 2016 - journals.plos.org
With the progress of optogenetics, the activities of genetically identified neurons can be
optically silenced to determine whether the neurons in question are necessary for the …

Potassium-selective channelrhodopsins

EG Govorunova, OA Sineshchekov… - Biophysics and …, 2023 - jstage.jst.go.jp
Since their discovery 21 years ago, channelrhodopsins have come of age and have become
indispensable tools for optogenetic control of excitable cells such as neurons and myocytes …

Kinetic characteristics of chimeric channelrhodopsins implicate the molecular identity involved in desensitization

A Zamani, S Sakuragi, T Ishizuka… - Biophysics and …, 2017 - jstage.jst.go.jp
Channelrhodopsin (ChR)-1 and ChR2 were the firstidentified members of ChRs which are a
growing subfamily of microbial-type rhodopsins. Light absorption drives the generation of a …

Express detection of water pollutants by photoelectric recording from algal cell suspensions

EG Govorunova, OA Sineshchekov - Bioassays, 2018 - Elsevier
Phototactic green algae, such as Chlamydomonas reinhardtii, generate photoinduced
channelrhodopsin-mediated currents across the cell membrane. These currents can be …

Molekularer Mechanismus protonenleitender Kanalrhodopsine und protonengekoppelte Zwei-Komponenten-Optogenetik

JTT Vierock - 2020 - edoc.hu-berlin.de
Kanalrhodopsine (ChRs) sind lichtaktivierte Ionenkanäle motiler Algen. Heterolog exprimiert
erlauben sie es, Ionenflüsse durch Licht zu steuern. Bevorzugt geleitet werden von den …