Modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: a systematic review and meta-analysis

TM Friebel, SM Domchek… - Journal of the National …, 2014 - academic.oup.com
Background There is substantial variability in cancer risk in women who have inherited a
BRCA1 or BRCA2 (BRCA1/2) mutation. Numerous factors have been hypothesized to …

Modifiable risk factors in women at high risk of breast cancer: a systematic review

SY Cohen, CR Stoll, A Anandarajah, M Doering… - Breast Cancer …, 2023 - Springer
Background Modifiable risk factors (alcohol, smoking, obesity, hormone use, and physical
activity) affect a woman's breast cancer (BC) risk. Whether these factors affect BC risk in …

BRCA Mutations and Breast Cancer Prevention

J Kotsopoulos - Cancers, 2018 - mdpi.com
Women who inherit a deleterious BRCA1 or BRCA2 mutation face substantially increased
risks of developing breast cancer, which is estimated at 70%. Although annual screening …

Alcohol intake and breast cancer risk: weighing the overall evidence

JA McDonald, A Goyal, MB Terry - Current breast cancer reports, 2013 - Springer
Moderate alcohol consumption has been linked to an approximate 30%–50% increased risk
in breast cancer. Case-control and cohort studies have consistently observed this modest …

Modifiers of breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers

RL Milne, AC Antoniou - Endocrine-related cancer, 2016 - erc.bioscientifica.com
Multiple endocrine neoplasia type 2 (MEN2) refers to the autosomal-dominant
neuroendocrine tumour syndromes, MEN type 2A (MEN2A) and MEN type 2B (MEN2B) …

[HTML][HTML] Contralateral breast cancer after radiotherapy among BRCA1 and BRCA2 mutation carriers: a WECARE study report

JL Bernstein, DC Thomas, RE Shore, M Robson… - European Journal of …, 2013 - Elsevier
Background Women with germline BRCA1 or BRCA2 (BRCA1/BRCA2) mutations are at
very high risk of developing breast cancer, including asynchronous contralateral breast …

Diagnostic and therapeutic ionizing radiation and the risk of a first and second primary breast cancer, with special attention for BRCA1 and BRCA2 mutation carriers: a …

JC Drooger, MJ Hooning, CM Seynaeve… - Cancer treatment …, 2015 - Elsevier
Occurrence of breast cancer is a well-known long-term side effect of ionizing radiation (both
diagnostic and therapeutic). The radiation-induced breast cancer risk increases with longer …

An overview on radiation sensitivity in hereditary breast and ovarian cancer syndrome

D Gonçalves, AS Pires, IA Marques, I Gomes, G Sousa… - Cancers, 2022 - mdpi.com
Simple Summary Individuals with hereditary breast and ovarian cancer (HBOC) syndrome
are more likely to develop several types of cancer compared to the general population. They …

The association between smoking and cancer incidence in BRCA1 and BRCA2 mutation carriers

KP Ko, SJ Kim, T Huzarski, J Gronwald… - … journal of cancer, 2018 - Wiley Online Library
Tobacco smoke is an established carcinogen, but the association between tobacco smoking
and cancer risk in BRCA mutation carriers is not clear. The aim of this study was to evaluate …

Full-exon pyrosequencing screening of BRCA germline mutations in Mexican women with inherited breast and ovarian cancer

F Vaca-Paniagua, RM Alvarez-Gomez… - PloS one, 2012 - journals.plos.org
Hereditary breast cancer comprises 10% of all breast cancers. The most prevalent genes
causing this pathology are BRCA1 and BRCA2 (breast cancer early onset 1 and 2), which …