FAPI PET: fibroblast activation protein inhibitor use in oncologic and nononcologic disease

Y Mori, K Dendl, J Cardinale, C Kratochwil, FL Giesel… - Radiology, 2023 - pubs.rsna.org
Gallium 68 (68Ga)–labeled fibroblast activation protein (FAP) inhibitor (FAPI) PET is based
on the molecular targeting of the FAP, which is known to be highly expressed in the major …

[HTML][HTML] Fibroblast activation protein-based theranostics in cancer research: a state-of-the-art review

L Zhao, J Chen, Y Pang, K Fu, Q Shang, H Wu… - Theranostics, 2022 - ncbi.nlm.nih.gov
In recent years, quinoline-based fibroblast activation protein (FAP) inhibitors (FAPI) have
shown promising results in the diagnosis of cancer and several other diseases, making them …

FAPI-PET/CT in cancer imaging: a potential novel molecule of the century

R Huang, Y Pu, S Huang, C Yang, F Yang, Y Pu… - Frontiers in …, 2022 - frontiersin.org
Fibroblast activation protein (FAP), a type II transmembrane serine protease, is highly
expressed in more than 90% of epithelial tumors and is closely associated with various …

Clinical summary of fibroblast activation protein inhibitor-based radiopharmaceuticals: cancer and beyond

M Li, MH Younis, Y Zhang, W Cai, X Lan - European journal of nuclear …, 2022 - Springer
Fibroblast activation protein (FAP) is a type II membrane-bound glycoprotein which is
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …

Current research topics in FAPI theranostics: a bibliometric analysis

AF van den Hoven, RGM Keijsers, MGEH Lam… - European Journal of …, 2023 - Springer
Purpose The study aimed to provide a comprehensive bibliometric overview of the current
scientific publications on fibroblast activation protein inhibitor (FAPI) positron emission …

Comparison of 68Ga-FAPI and 18F-FDG PET/CT in the Evaluation of Patients With Newly Diagnosed Non-Small Cell Lung Cancer

J Wu, H Deng, H Zhong, T Wang, Z Rao, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Purpose Several studies have demonstrated that 68Ga-FAPI PET/CT shows high
intratumoral tracer uptake and low normal tissue uptake, allowing for excellent visualization …

The performance of 68Ga-FAPI-04 PET/CT in head and neck squamous cell carcinoma: a prospective comparison with 18F-FDG PET/CT

Y Jiang, B Wen, C Li, Y Tian, Z Xiao, K Xu… - European Journal of …, 2023 - Springer
Purpose This study was designed to compare the performance of 68Ga-FAPI-04 and 18F-
FDG PET/CT for initial staging and recurrence detection of head and neck squamous cell …

Head-to-head comparison of FDG and radiolabeled FAPI PET: a systematic review of the literature

P Guglielmo, P Alongi, L Baratto, E Abenavoli… - Life, 2023 - mdpi.com
FAPI-based radiopharmaceuticals are a novel class of tracers, mainly used for PET imaging,
which have demonstrated several advantages over [18F] FDG, especially in the case of low …

The superiority of fibroblast activation protein inhibitor (FAPI) PET/CT versus FDG PET/CT in the diagnosis of various malignancies

Y Dong, H Zhou, A Alhaskawi, Z Wang, J Lai, C Yao… - Cancers, 2023 - mdpi.com
Simple Summary Fibroblast activation protein is a newly discovered biomarker in various
tumor types. Using inhibitors ligated with radiopharmaceuticals, nuclear medicine …

Diagnostic Accuracy of [68Ga]Ga Labeled Fibroblast-Activation Protein Inhibitors in Detecting Head and Neck Cancer Lesions Using Positron Emission Tomography …

A Rizzo, A Miceli, M Racca, M Bauckneht, S Morbelli… - Pharmaceuticals, 2023 - mdpi.com
Several studies have examined the use of positron emission tomography (PET) using [68Ga]
Ga-radiolabeled fibroblast-activation protein inhibitors (FAPi) across multiple subtypes of …