Protein design: From the aspect of water solubility and stability

R Qing, S Hao, E Smorodina, D Jin, A Zalevsky… - Chemical …, 2022 - ACS Publications
Water solubility and structural stability are key merits for proteins defined by the primary
sequence and 3D-conformation. Their manipulation represents important aspects of the …

Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental …

SK Burley, C Bhikadiya, C Bi, S Bittrich… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB), the US data center for the global PDB archive and a founding member of the …

DBAASP v3: database of antimicrobial/cytotoxic activity and structure of peptides as a resource for development of new therapeutics

M Pirtskhalava, AA Amstrong, M Grigolava… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is an
open-access, comprehensive database containing information on amino acid sequences …

RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy

SK Burley, HM Berman, C Bhikadiya, C Bi… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB, rcsb. org), the US data center for the global PDB archive, serves thousands of Data …

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database

B Jia, AR Raphenya, B Alcock… - Nucleic acids …, 2016 - academic.oup.com
Abstract The Comprehensive Antibiotic Resistance Database (CARD; http://arpcard.
mcmaster. ca) is a manually curated resource containing high quality reference data on the …

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

H Ashkenazy, S Abadi, E Martz, O Chay… - Nucleic acids …, 2016 - academic.oup.com
The degree of evolutionary conservation of an amino acid in a protein or a nucleic acid in
DNA/RNA reflects a balance between its natural tendency to mutate and the overall need to …

The RCSB protein data bank: integrative view of protein, gene and 3D structural information

PW Rose, A Prlić, A Altunkaya, C Bi… - Nucleic acids …, 2016 - academic.oup.com
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB, http://rcsb. org), the US data center for the global PDB archive, makes PDB data freely …

The BioGRID interaction database: 2017 update

A Chatr-Aryamontri, R Oughtred, L Boucher… - Nucleic acids …, 2017 - academic.oup.com
Abstract The Biological General Repository for Interaction Datasets (BioGRID:
https://thebiogrid. org) is an open access database dedicated to the annotation and archival …

THPdb: Database of FDA-approved peptide and protein therapeutics

SS Usmani, G Bedi, JS Samuel, S Singh, S Kalra… - PloS one, 2017 - journals.plos.org
THPdb (http://crdd. osdd. net/raghava/thpdb/) is a manually curated repository of Food and
Drug Administration (FDA) approved therapeutic peptides and proteins. The information in …