[HTML][HTML] Endothelial cell calcium signaling during barrier function and inflammation

PJ Dalal, WA Muller, DP Sullivan - The American journal of pathology, 2020 - Elsevier
Calcium is an essential second messenger in endothelial cells and plays a pivotal role in
regulating a number of physiologic processes, including cell migration, angiogenesis …

Differential regulation of inducible and endothelial nitric oxide synthase by kinin B1 and B2 receptors

F Kuhr, J Lowry, Y Zhang, V Brovkovych, RA Skidgel - Neuropeptides, 2010 - Elsevier
Kinins are vasoactive peptides that play important roles in cardiovascular homeostasis, pain
and inflammation. After release from their precursor kininogens, kinins or their C-terminal …

Complex heterogeneous tissue constructs containing multiple cell types prepared by inkjet printing technology

T Xu, W Zhao, JM Zhu, MZ Albanna, JJ Yoo, A Atala - Biomaterials, 2013 - Elsevier
This study was designed to develop a versatile method for fabricating complex and
heterogeneous three-dimensional (3D) tissue constructs using simultaneous ink-jetting of …

Gαq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin

I Singh, N Knezevic, GU Ahmmed, V Kini… - Journal of Biological …, 2007 - ASBMB
RhoA activation and increased intracellular Ca 2+ concentration mediated by the activation
of transient receptor potential channels (TRPC) both contribute to the thrombin-induced …

TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response

EW Weber, F Han, M Tauseef, L Birnbaumer… - Journal of Experimental …, 2015 - rupress.org
Leukocyte transendothelial migration (TEM) is a tightly regulated, multistep process that is
critical to the inflammatory response. A transient increase in endothelial cytosolic free …

Store-Operated Ca2+ Entry Is Remodelled and Controls In Vitro Angiogenesis in Endothelial Progenitor Cells Isolated from Tumoral Patients

F Lodola, U Laforenza, E Bonetti, D Lim, S Dragoni… - 2012 - journals.plos.org
Background Endothelial progenitor cells (EPCs) may be recruited from bone marrow to
sustain tumor vascularisation and promote the metastatic switch. Understanding the …

Orai1 mediates the interaction between STIM1 and hTRPC1 and regulates the mode of activation of hTRPC1-forming Ca2+ channels

I Jardin, JJ Lopez, GM Salido, JA Rosado - Journal of biological chemistry, 2008 - ASBMB
Orai1 and hTRPC1 have been presented as essential components of store-operated
channels mediating highly Ca 2+ selective I CRAC and relatively Ca 2+ selective I SOC …

[HTML][HTML] Update on vascular endothelial Ca2+ signalling: A tale of ion channels, pumps and transporters

F Moccia, R Berra-Romani, F Tanzi - World journal of biological …, 2012 - ncbi.nlm.nih.gov
A monolayer of endothelial cells (ECs) lines the lumen of blood vessels and forms a
multifunctional transducing organ that mediates a plethora of cardiovascular processes. The …

[HTML][HTML] TRP channels in endothelial function and dysfunction

HY Kwan, Y Huang, X Yao - … et Biophysica Acta (BBA)-Molecular Basis of …, 2007 - Elsevier
Endothelial cells produce various factors that regulate vascular tone, vascular permeability,
angiogenesis, and inflammatory responses. The dysfunction of endothelial cells is believed …

Implication of the Kallikrein-Kinin system in neurological disorders: Quest for potential biomarkers and mechanisms

A Nokkari, H Abou-El-Hassan, Y Mechref… - Progress in …, 2018 - Elsevier
Neurological disorders represent major health concerns in terms of comorbidity and
mortality worldwide. Despite a tremendous increase in our understanding of the …