Immunotherapy is regarded as the most promising treatment for cancers. Various cancer
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …

Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …

The maternal-fetal interface undergoes dynamic changes to allow the fetus to grow and
develop in the uterus, despite being recognized by the maternal immune cells. Within the …

The purpose of immunology is simple. Cure or prevent disease. M1/M2 is useful because it
is simple. M1/M2 describes the two major and opposing activities of macrophages. M1 …

Macrophages are abundant in almost all tissues of all multicellular organisms, estimated to
total 10 10 cells in adult humans. Macrophage function is essential for health, as strikingly …

M1 and M2 macrophage-type responses kill or repair in vivo. The unique ability of
macrophages to make these polar opposite type of responses provides primary host …

Simple Summary Human health is significantly affected by microbial infections. One of the
largest determinants of the outcomes of such infections is the host immune response. Too …

Successful immunotherapy of cancer is becoming a reality aided by the realization that
macrophages play an important role in the growth or regression of tumors. Specifically …

The purpose of this perspective is to describe a critical advance in understanding how
immune responses work. Macrophages are required for all animal life:'Inhibit'type …

The foreign body reaction (FBR) is a response of the host tissue against more or less
degradation-resistant foreign macromolecular material. The reaction is divided into five …