Tetrazole derivatives are a prime class of heterocycles, very important to medicinal
chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide …

The term functionalized isocyanides refers to all those isocyanides in which a neighbouring
functional group can finely tune the reactivity of the isocyano group or can be exploited in …

This short review compiles the main results of the studies in tetrazole chemistry published in
the period 2009–2016. Attention is directed to the structure, reactivity, synthetic problems …

Benzodiazepines (BZDs), a diverse class of benzofused seven-membered N-heterocycles,
display essential pharmacological properties and play vital roles in some biochemical …

Reaction rate acceleration using green methods is an intriguing area of research for
chemists. In this regard, water as a “green solvent” plays a crucial role in the acceleration of …

The efficacy of isocyanide reactions in the synthesis of natural or naturallike products has
resulted in a renaissance of isocyanide chemistry. Now isocyanides are widely used in …

The aim of this review is providing an overview of the various representative literature
procedures for the preparation of tetrazoles via isocyanide-based reactions. These reactions …

The development of new synthetic approaches to the 1, 4-benzodiazepine ring system and
their further elaboration have provided access to a broad range of functionalized derivatives …

Benzodiazepines, seven-membered heterocyclic compounds having two nitrogen atoms at
different positions, are ruling scaffolds in the area of pharmaceutical industry. They act as …

Isocyanides were formally discovered by Gautier1 and Hofmann2 in 1867 but the history of
isocyanide chemistry in fact predates this discovery. Lieke carried out the first isocyanide …