Long-term survival after kidney transplantation

S Hariharan, AK Israni… - New England Journal of …, 2021 - Mass Medical Soc
Long-Term Survival after Kidney Transplantation This review discusses demographics,
survival, and risks in kidney transplantation since the mid-1990s. It addresses postoperative …

[HTML][HTML] Significance of HLA-DQ in kidney transplantation: time to reevaluate human leukocyte antigen–matching priorities to improve transplant outcomes? An expert …

AR Tambur, V Kosmoliaptsis, FHJ Claas, RB Mannon… - Kidney international, 2021 - Elsevier
The weight of human leukocyte antigen (HLA) matching in kidney allocation algorithms,
especially in the United States, has been devalued in a stepwise manner, supported by the …

Eplet mismatch load and de novo occurrence of donor-specific anti-HLA antibodies, rejection, and graft failure after kidney transplantation: an observational cohort …

A Senev, M Coemans, E Lerut… - Journal of the …, 2020 - journals.lww.com
Background In kidney transplantation, evaluating mismatches of HLA eplets—small patches
of surface-exposed amino acids of the HLA molecule—instead of antigen mismatches might …

[HTML][HTML] Sensitization in transplantation: assessment of risk 2022 working group meeting report

AR Tambur, O Bestard, P Campbell, AS Chong… - American Journal of …, 2023 - Elsevier
Abstract The Sensitization in Transplantation: Assessment of Risk workgroup is a
collaborative effort of the American Society of Transplantation and the American Society of …

Translating B cell immunology to the treatment of antibody-mediated allograft rejection

PS Heeger, MC Haro, S Jordan - Nature Reviews Nephrology, 2024 - nature.com
Abstract Antibody-mediated rejection (AMR), including chronic AMR (cAMR), causes~ 50%
of kidney allograft losses each year. Despite attempts to develop well-tolerated and effective …

[HTML][HTML] The negative impact of T cell–mediated rejection on renal allograft survival in the modern era

C Rampersad, R Balshaw, IW Gibson, J Ho… - American Journal of …, 2022 - Elsevier
The prevalence and long-term impact of T cell–mediated rejection (TCMR) is poorly defined
in the modern era of tacrolimus/mycophenolate-based maintenance therapy. This …

The therapeutic challenge of late antibody‐mediated kidney allograft rejection

GA Böhmig, F Eskandary, K Doberer… - Transplant …, 2019 - Wiley Online Library
Late antibody‐mediated rejection (ABMR) is a cardinal cause of kidney allograft failure,
manifesting as a continuous and, in contrast with early rejection, often clinically silent …

[HTML][HTML] Sensitization in transplantation: assessment of risk (STAR) 2019 working group meeting report

AR Tambur, P Campbell, AS Chong, S Feng… - American Journal of …, 2020 - Elsevier
The purpose of the STAR 2019 Working Group was to build on findings from the initial STAR
report to further clarify the expectations, limitations, perceptions, and utility of alloimmune …

A comprehensive evaluation of the antibody-verified status of eplets listed in the HLA epitope registry

S Bezstarosti, KH Bakker, CSM Kramer… - Frontiers in …, 2022 - frontiersin.org
Matching strategies based on HLA eplets instead of HLA antigens in solid organ
transplantation may not only increase the donor pool for highly sensitized patients, but also …

Incidence, risk factors, treatment, and consequences of antibody‐mediated kidney transplant rejection: a systematic review

A Hart, D Singh, SJ Brown, JH Wang… - Clinical …, 2021 - Wiley Online Library
Background Antibody‐mediated rejection (AMR) is a leading cause of kidney allograft
failure, but its incidence, risk factors, and outcomes are not well understood. Methods We …