M Xie, X Wang, Z Duan, G Luan - Frontiers in Neuroscience, 2023 - frontiersin.org
Brain tumors can always result in seizures when involving the cortical neurons or their circuits, and they were found to be one of the most common etiologies of intractable focal …
Objective This study aimed at estimating the cumulative incidence of antiepileptic drug (AED) treatment failure of first‐line monotherapy levetiracetam vs valproic acid in glioma …
A Coppola, A Zarabla, A Maialetti, V Villani… - Frontiers in …, 2020 - frontiersin.org
Background: Epilepsy is one of the most common symptoms of brain tumors. It is often drug resistant and generally worsen patients' quality of life (QoL). Brain tumors release glutamate …
TF Ersoy, S Ridwan, A Grote, R Coras, M Simon - Scientific Reports, 2020 - nature.com
Early postoperative seizures (EPS) are a common complication of brain tumour surgery. This paper investigates risk factors, management and clinical relevance of EPS. We …
Objective This study aimed to directly compare the effectiveness of first‐line monotherapy levetiracetam (LEV) versus enzyme‐inducing antiseizure medications (EIASMs) in glioma …
T Ius, G Pauletto, B Tomasino, M Maieron, R Budai… - Cancers, 2020 - mdpi.com
The importance of the extent of resection (EOR) has been widely demonstrated as the main predictor for survival, nevertheless its effect on tumor related epilepsy is less investigated. A …
Patients affected with gliomas develop a complex set of clinical manifestations that deeply impact on quality of life and overall survival. Brain tumor-related epilepsy is frequently the …
R Rudà, C Houillier, M Maschio, JC Reijneveld… - …, 2020 - Wiley Online Library
Objective To evaluate the effectiveness and tolerability of lacosamide added to one or two antiepileptic drugs (AEDs) in the treatment of patients with brain tumor–related epilepsy …
M Stella, G Baiardi, S Pasquariello, F Sacco… - Biomedicines, 2023 - mdpi.com
Glioblastoma (GBM) is characterized by fast-growing cells, genetic and phenotypic heterogeneity, and radio-chemo-therapy resistance, contributing to its dismal prognosis …