Thermodynamic bound on the asymmetry of cross-correlations

N Ohga, S Ito, A Kolchinsky - Physical Review Letters, 2023 - APS
The principle of microscopic reversibility says that, in equilibrium, two-time cross-correlations
are symmetric under the exchange of observables. Thus, the asymmetry of cross …

Cell sorting using a high throughput fluorescence flow cytometer

E Diebold, K Owsley, J Lin - US Patent 10,324,019, 2019 - Google Patents
In one aspect, a method of sorting cells in a flow cytometry system is disclosed, which
includes illuminating a cell with radiation having at least two optical frequencies shifted from …

Statistics and related topics in single-molecule biophysics

H Qian, SC Kou - Annual review of statistics and its application, 2014 - annualreviews.org
Since the universal acceptance of atoms and molecules as the fundamental constituents of
matter in the early-twentieth century, molecular physics, chemistry, and molecular biology …

Assembly of the transcription machinery: ordered and stable, random and dynamic, or both?

TJ Stasevich, JG McNally - Chromosoma, 2011 - Springer
The assembly of the transcription machinery is a key step in gene activation, but even basic
details of this process remain unclear. Here we discuss the apparent discrepancy between …

Dissipation, quantum coherence, and asymmetry of finite-time cross-correlations

T Van Vu, VT Vo, K Saito - Physical Review Research, 2024 - APS
Recent studies have revealed a deep connection between the asymmetry of cross-
correlations and thermodynamic quantities in the short-time limit. In this study, we address …

STICCS reveals matrix-dependent adhesion slipping and gripping in migrating cells

T Toplak, E Pandzic, L Chen, M Vicente-Manzanares… - Biophysical journal, 2012 - cell.com
Two-color spatio-temporal image cross-correlation spectroscopy (STICCS) is a new, to our
knowledge, image analysis method that calculates space-time autocorrelation and cross …

Quantitation of ten 30S ribosomal assembly intermediates using fluorescence triple correlation spectroscopy

WK Ridgeway, DP Millar… - Proceedings of the …, 2012 - National Acad Sciences
The self-assembly of bacterial 30S ribosomes involves a large number of RNA folding and
RNA-protein binding steps. The sequence of steps determines the overall assembly …

Quantifying histone and RNA polymerase II post-translational modification dynamics in mother and daughter cells

TJ Stasevich, Y Sato, N Nozaki, H Kimura - Methods, 2014 - Elsevier
Post-translational histone modifications are highly correlated with transcriptional activity, but
the relative timing of these marks and their dynamic interplay during gene regulation …

Evaluation of reaction fluxes in stationary and oscillating far-from-equilibrium biological systems

C Bianca, A Lemarchand - Physica A: Statistical Mechanics and its …, 2015 - Elsevier
The complex spatio-temporal structures that appear in chemical and biological systems
require far-from-equilibrium conditions which may lead to the circulation of reaction fluxes …

Spatio-temporal coordination among functional residues in protein

S Dutta, M Ghosh, J Chakrabarti - Scientific Reports, 2017 - nature.com
The microscopic basis of communication among the functional sites in bio-macromolecules
is a fundamental challenge in uncovering their functions. We study the communication …