Embelin inhibits viability of cutaneous T cell lymphoma cell lines HuT78 and H9 by targeting inhibitors of apoptosis

N Abdulrahman, R Leo, HA Boumenar… - Leukemia & …, 2023 - Taylor & Francis
Cutaneous T cell lymphoma (CTCL) is a varied group of neoplasms that affects the skin.
Acquired resistance against chemotherapeutic drugs and associated toxic side effects are …

Combined inhibition of XIAP and autophagy induces apoptosis and differentiation in acute myeloid leukaemia

Z Huang, J Zhou, Y Jiang, Y Han… - Journal of Cellular …, 2023 - Wiley Online Library
Perturbations in autophagy, apoptosis and differentiation have greatly affected the
progression and therapy of acute myeloid leukaemia (AML). The role of X‐linked inhibitor of …

[HTML][HTML] The survivin/XIAP suppressant YM155 impairs clonal growth and induces apoptosis in JAK2V617F cells

JAEG Carlos, K Lima, EM Rego… - … , Transfusion and Cell …, 2024 - Elsevier
The central role of the control of apoptosis in the pathophysiology of Philadelphia
chromosome-negative myeloproliferative neoplasms has recently been reinforced in genetic …

CRISPR-Cas9 Mediated AGO2 Knockout inhibits tumorigenesis in human colorectal cancer cells

Y Zhu, G Wang, H Xu, Y Guo - Cellular and Molecular Biology, 2024 - mail.cellmolbiol.org
AGO2 plays a vital role in small RNA-guided gene silencing, which has been implied in the
tumorigenesis of different types of tumors. Fundamentally, increased expression of AGO2 …