Arachidonic acid metabolism and kidney inflammation
As a major component of cell membrane lipids, Arachidonic acid (AA), being a major
component of the cell membrane lipid content, is mainly metabolized by three kinds of …
component of the cell membrane lipid content, is mainly metabolized by three kinds of …
COVID-19 and diabetes mellitus: how one pandemic worsens the other
In light of the most challenging public health crisis of modern history, COVID-19 mortality
continues to rise at an alarming rate. Patients with co-morbidities such as hypertension …
continues to rise at an alarming rate. Patients with co-morbidities such as hypertension …
Vascular actions of 20-HETE
hydroxyeicosatetraenoic acid (20-HETE) is a metabolite of arachidonic acid that exhibits a
myriad of biological effects in the vascular system. This review discusses the current …
myriad of biological effects in the vascular system. This review discusses the current …
Cytochrome P450 eicosanoids in hypertension and renal disease
Cytochrome P450 eicosanoids in hypertension and renal diseas... : Current Opinion in
Nephrology and Hypertension Cytochrome P450 eicosanoids in hypertension and renal disease …
Nephrology and Hypertension Cytochrome P450 eicosanoids in hypertension and renal disease …
Effect of cytochrome P450 metabolites of arachidonic acid in nephrology
Thirty-five years ago, a third pathway for the metabolism of arachidonic acid by cytochrome
P450 enzymes emerged. Subsequent work revealed that 20-hydroxyeicosatetraenoic and …
P450 enzymes emerged. Subsequent work revealed that 20-hydroxyeicosatetraenoic and …
Novel insights into redox system and the mechanism of redox regulation
X Wang, C Hai - Molecular Biology Reports, 2016 - Springer
In view of the critical role of redox system in numerous physiological and pathophysiological
processes, it is important to clearly understand the family members and regulatory …
processes, it is important to clearly understand the family members and regulatory …
Arachidonic acid metabolism as a therapeutic target in AKI-to-CKD transition
XJ Li, P Suo, YN Wang, L Zou, XL Nie… - Frontiers in …, 2024 - frontiersin.org
Arachidonic acid (AA) is a main component of cell membrane lipids. AA is mainly
metabolized by three enzymes: cyclooxygenase (COX), lipoxygenase (LOX) and …
metabolized by three enzymes: cyclooxygenase (COX), lipoxygenase (LOX) and …
mTORC2 signaling regulates Nox4-induced podocyte depletion in diabetes
S Eid, S Boutary, K Braych, R Sabra… - Antioxidants & redox …, 2016 - liebertpub.com
Aim: Podocyte apoptosis is a critical mechanism for excessive loss of urinary albumin that
eventuates in kidney fibrosis. Oxidative stress plays a critical role in hyperglycemia-induced …
eventuates in kidney fibrosis. Oxidative stress plays a critical role in hyperglycemia-induced …
20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance
A Gilani, K Agostinucci, S Hossain, JV Pascale… - Prostaglandins & other …, 2021 - Elsevier
HETE, a metabolite of arachidonic acid produced by Cytochrome P450 (CYP) 4A/4 F, has
been implicated in the development of obesity-associated complications such as diabetes …
been implicated in the development of obesity-associated complications such as diabetes …
Peri-renal adipose inflammation contributes to renal dysfunction in a non-obese prediabetic rat model: Role of anti-diabetic drugs
Diabetic nephropathy is a major health challenge with considerable economic burden and
significant impact on patients' quality of life. Despite recent advances in diabetic patient care …
significant impact on patients' quality of life. Despite recent advances in diabetic patient care …