Mammalian sperm cells must respond to cues originating from along the female
reproductive tract and from the layers of the egg in order to complete their fertilization …

A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …

Physiological changes that endow mammalian sperm with fertilizing capacity are known as
sperm capacitation. As part of capacitation, sperm develop an asymmetrical flagellar beating …

Sexually reproducing animals require an orchestrated communication between
spermatozoa and the egg to generate a new individual. Capacitation, a maturational …

Fertilization is defined as the process of union of two germ cells, egg and sperm, whereby
the somatic chromosome number is restored and the development of a new individual …

Because it is generally accepted that a high percentage of poorly motile or immotile sperm
will adversely affect male fertility, analysis of sperm motility is a central part of the evaluation …

Capacitation is a complex series of molecular events that occurs in sperm after epididymal
maturation and confers on sperm the ability to fertilize an egg. This process can be mimicked …

Fertilization is a matter of life or death. In animals of sexual reproduction, the appropriate
communication between mature and competent male and female gametes determines the …

Potassium channels have evolved to play specialized roles in both excitable and inexcitable
tissues. Here we describe the cloning and expression of Slo3, a novel potassium channel …

A number of physiological events, such as sperm hyperactivation, chemotaxis towards the
egg, capacitation and acrosome reaction, are triggered by activation of sperm ion channels …