Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …

The innate immune response was once considered to be a limited set of responses that
aimed to contain an infection by primitive'ingest and kill'mechanisms, giving the host time to …

Candida auris is a multidrug-resistant human fungal pathogen responsible for nosocomial
outbreaks worldwide. Although considerable progress has increased our understanding of …

Neutrophils phagocytose and kill microbes upon phagolysosomal fusion. Recently we found
that activated neutrophils form extracellular fibres that consist of granule proteins and …

The topic of immunity to fungal infections is of interest to a wide range of disciplines, from
microbiology to immunology. It is of particular interest in terms of therapy of HIV-infected …

Dectin-1 is a C-type lectin involved in the recognition of β-glucans found in the cell walls of
fungi. We generated dectin-1-deficient mice to determine the importance of dectin-1 in the …

Cryptococcus neoformans (Cn) is an encapsulated yeast that is a facultative intracellular
pathogen and a frequent cause of human disease. The interaction of Cn with alveolar …

In vitro studies have indicated the importance of Toll-like receptor (TLR) signaling in
response to the fungal pathogens Candida albicans and Aspergillus fumigatus. However …

The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Mammalian innate immune cells produce reactive oxygen species (ROS) in the oxidative
burst reaction to destroy invading microbial pathogens. Using quantitative real‐time ROS …