Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …

Network pharmacology is an emerging area of systematic drug research that attempts to
understand drug actions and interactions with multiple targets. Network pharmacology has …

At present, the uptake and accumulation of nanoplastics by plants have raised particular
concerns. However, molecular mechanisms underlying nanoplastic phytotoxicity are still …

Recent developments in immuno-oncology demonstrate that not only cancer cells, but also
the tumor microenvironment can guide precision medicine. A comprehensive and in-depth …

Intrahepatic cholangiocarcinoma (ICC) is a malignant tumor derived from bile duct
epithelium. Its characteristics include an insidious onset and frequent recurrence or …

Halophenolic disinfection byproducts (DBPs) are a class of emerging pollutants whose
adverse effects on human cells and the underlying molecular mechanisms still need further …

Transcytosis of polymeric IgA and IgM from the basolateral surface to the apical side of the
epithelium and subsequent secretion into mucosal fluids are mediated by the polymeric …

Breast cancer is one of the leading causes of cancer-associated mortality in women
worldwide and has become a major public health problem. Although the definitive cause of …

Glioblastoma multiforme (GBM) is the most malignant and lethal primary brain tumor in
adults accounting for about 50% of all gliomas. The only treatment available for GBM is the …

Abstract Non-Small Cell Lung Cancer (NSCLC) exhibits intrinsic heterogeneity at the
molecular level that aids in distinguishing between its two prominent subtypes—Lung …