Cancer-associated venous thromboembolism

AA Khorana, N Mackman, A Falanga… - Nature reviews Disease …, 2022 - nature.com
Cancer-associated thrombosis (including venous thromboembolism (VTE) and arterial
events) is highly consequential for patients with cancer and is associated with worsened …

Updates in the incidence, pathogenesis, and management of cancer and venous thromboembolism

L Girardi, TF Wang, W Ageno… - … Thrombosis, and Vascular …, 2023 - Am Heart Assoc
Patients with cancer are at higher risk of developing venous thromboembolism (VTE)
compared with the general population. This elevated risk is due to several risk factors and …

[HTML][HTML] Hemostasis and cancer: Impact of haemostatic biomarkers for the prediction of clinical outcomes in patients with cancer

F Moik, C Ay - Journal of Thrombosis and Haemostasis, 2022 - Elsevier
Patients with cancer are characterized by a dysregulation of the hemostatic system and
systemic hypercoagulability. Different components of the hemostatic system are involved in …

Histopathological features of cancer-associated venous thromboembolism: presence of intrathrombus cancer cells and prothrombotic factors

T Gi, A Kuwahara, A Yamashita, S Matsuda… - … and Vascular Biology, 2023 - Am Heart Assoc
Background: Cancer-associated venous thromboembolism (VTE) is a critical complication in
patients with cancer. However, the pathological findings of VTE are limited. Here, we …

Reducing oxidative protein folding alleviates senescence by minimizing ER‐to‐nucleus H2O2 release

F Cheng, Q Ji, L Wang, C Wang, GH Liu, L Wang - EMBO reports, 2023 - embopress.org
Oxidative protein folding occurs in the endoplasmic reticulum (ER) to generate disulfide
bonds, and the by‐product is hydrogen peroxide (H2O2). However, the relationship between …

Venous and arterial thromboembolism in patients with cancer treated with targeted anti-cancer therapies

F Moik, C Ay - Thrombosis Research, 2022 - Elsevier
Patients with cancer have an increased risk of venous-and arterial thromboembolism
(VTE/ATE). Anti-cancer treatments including surgery, radiotherapy, and certain …

Hemostatic biomarkers and venous thromboembolism are associated with mortality and response to chemotherapy in patients with pancreatic cancer

F Moik, G Prager, J Thaler, F Posch… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Pancreatic cancer activates coagulation and increases risk of venous
thromboembolism (VTE). We aimed at characterizing the association of hemostatic …

Immunothrombosis and vascular heterogeneity in cerebral cavernous malformation

MA Globisch, FC Onyeogaziri… - Blood, The Journal …, 2022 - ashpublications.org
Cerebral cavernous malformation (CCM) is a neurovascular disease that results in various
neurological symptoms. Thrombi have been reported in surgically resected CCM patient …

Pro-tumorigenic and thrombotic activities of platelets in Lung Cancer

R Anderson, BL Rapoport, HC Steel… - International Journal of …, 2023 - mdpi.com
Aside from their key protective roles in hemostasis and innate immunity, platelets are now
recognized as having multifaceted, adverse roles in the pathogenesis, progression and …

[PDF][PDF] More pronounced hypercoagulable state and hypofibrinolysis in patients with cirrhosis with versus without HCC

A Zanetto, E Campello, C Bulato… - Hepatology …, 2021 - Wiley Online Library
In patients with cirrhosis, particularly those with hepatocellular carcinoma (HCC),
hypercoagulability may be associated with purported increased risks of portal vein …