Nano-enhanced drug delivery and therapeutic ultrasound for cancer treatment and beyond

P Tharkar, R Varanasi, WSF Wong, CT Jin… - … in Bioengineering and …, 2019 - frontiersin.org
While ultrasound is most widely known for its use in diagnostic imaging, the energy carried
by ultrasound waves can be utilized to influence cell function and drug delivery …

Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications

VA Khokhlova, JB Fowlkes, WW Roberts… - International journal …, 2015 - Taylor & Francis
In high intensity focused ultrasound (HIFU) therapy, an ultrasound beam is focused within
the body to locally affect the targeted site without damaging intervening tissues. The most …

Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions

N Rapoport, KH Nam, R Gupta, Z Gao, P Mohan… - Journal of Controlled …, 2011 - Elsevier
Perfluorocarbon nanoemulsions can deliver lipophilic therapeutic agents to solid tumors and
simultaneously provide for monitoring nanocarrier biodistribution via ultrasonography and/or …

Immuno-thermal ablations–boosting the anticancer immune response

R Slovak, JM Ludwig, SN Gettinger, RS Herbst… - … for immunotherapy of …, 2017 - Springer
The use of immunomodulation to treat malignancies has seen a recent explosion in interest.
The therapeutic appeal of these treatments is far reaching, and many new applications …

Phase‐shift, stimuli‐responsive perfluorocarbon nanodroplets for drug delivery to cancer

N Rapoport - Wiley Interdisciplinary Reviews: Nanomedicine …, 2012 - Wiley Online Library
This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …

Novel delivery approaches for cancer therapeutics

AK Mitra, V Agrahari, A Mandal, K Cholkar… - Journal of controlled …, 2015 - Elsevier
Currently, a majority of cancer treatment strategies are based on the removal of tumor mass
mainly by surgery. Chemical and physical treatments such as chemo-and radiotherapies …

Chitin, chitosan, and glycated chitosan regulate immune responses: the novel adjuvants for cancer vaccine

X Li, M Min, N Du, Y Gu, T Hode… - Journal of …, 2013 - Wiley Online Library
With the development of cancer immunotherapy, cancer vaccine has become a novel
modality for cancer treatment, and the important role of adjuvant has been realized recently …

[HTML][HTML] Hyperthermia as an immunotherapy strategy for cancer

JJ Skitzki, EA Repasky, SS Evans - Current opinion in …, 2009 - ncbi.nlm.nih.gov
The use of hyperthermia as an adjunct to cancer immunotherapy is supported by an
increasing number of research data. Both preclinical and clinical data results have …

[PDF][PDF] The tumor microenvironment and immunotherapy in prostate and bladder cancer

SS Nair, R Weil, Z Dovey, A Davis, AK Tewari - Urologic Clinics of North …, 2020 - Elsevier
Acknowledgements: The authors wish to thank Sima Rabinowitz, SR for editorial assistance.
The authors wish to acknowledge funding support from the Deane Prostate Health, ISMMS …

Biomaterial scaffold-based local drug delivery systems for cancer immunotherapy

C Yang, NT Blum, J Lin, J Qu, P Huang - Science Bulletin, 2020 - Elsevier
Immunotherapy has attracted tremendous attention due to the remarkable clinical successes
for treating a broad spectrum of tumors. One challenge for cancer immunotherapy is the …