Wilms tumour

F Spreafico, CV Fernandez, J Brok, K Nakata… - Nature Reviews …, 2021 - nature.com
Wilms tumour (WT) is a childhood embryonal tumour that is paradigmatic of the intersection
between disrupted organogenesis and tumorigenesis. Many WT genes play a critical (non …

Prognostic factors for Wilms tumor recurrence: a review of the literature

A Groenendijk, F Spreafico, RR de Krijger, J Drost… - Cancers, 2021 - mdpi.com
Simple Summary A Wilms tumor is a childhood kidney tumor. In high-income countries, 90%
of patients with this tumor survive. However, the tumor recurs in 15% of patients. It is …

Pediatric renal tumor epidemiology: Global perspectives, progress, and challenges

J Libes, J Hol, JCA Neto, KL Vallance… - Pediatric blood & …, 2023 - Wiley Online Library
Pediatric renal tumors account for 3%–11% of childhood cancers, the most common of
which is Wilms tumor or nephroblastoma. Epidemiology plays a key role in cancer …

Advances in the clinical management of high‐risk Wilms tumors

MV Ortiz, C Koenig, AE Armstrong, J Brok… - Pediatric blood & …, 2023 - Wiley Online Library
Outcomes are excellent for the majority of patients with Wilms tumors (WT). However, there
remain WT subgroups for which the survival rate is approximately 50% or lower …

Treatment abandonment: A report from the collaborative African network for childhood cancer care and research—CANCaRe Africa

G Chagaluka, GM Afungchwi, L Landman… - Pediatric Blood & …, 2021 - Wiley Online Library
Background 'Treatmentabandonment'is a common and preventable cause of childhood
cancer treatment failure in low‐and middle‐income countries (LMIC). Risk factors and …

Effectiveness of a Wilms tumour treatment guideline adapted to local circumstances in sub‐Saharan Africa: A report from Wilms Africa Phase II—CANCaRe Africa

D Fufa, C Mdoka, M Ayalew, H Khofi… - Pediatric Blood & …, 2024 - Wiley Online Library
Background Wilms tumour (WT) is one of the cancer types targeted by the Global Initiative
for Childhood Cancer (GICC). The objective of this study was to describe the outcomes of …

Surgical aspects and outcomes after nephrectomy for Wilms tumour in sub‐Saharan Africa: A report from Wilms Africa Phase II—CANCaRe Africa

W Appeadu‐Mensah, C Mdoka, S Alemu… - Pediatric Blood & …, 2025 - Wiley Online Library
Background Wilms tumour (WT) is one of the common and curable cancer types targeted by
the Global Initiative for Childhood Cancer. Tumour excision is essential for cure. This …

[HTML][HTML] Working together to build a better future for children with cancer in Africa

I Chitsike, V Paintsil, L Sung, F Njuguna… - JCO global …, 2020 - ncbi.nlm.nih.gov
There has been substantial improvement in survival of children with cancer in high-income
countries. However, great challenges remain in low-and middleincome countries, where …

Wilms tumor in Sub-Saharan Africa: molecular and social determinants of a global pediatric health disparity

A Apple, HN Lovvorn III - Frontiers in Oncology, 2020 - frontiersin.org
Wilms tumor (WT) is the most common renal malignancy of childhood. Global disparities in
WT have been reported with the highest incidence and lowest overall survival occurring in …

Outcomes of Wilms tumor treatment in western Kenya

A Uittenboogaard, F Njuguna, S Mostert… - Pediatric Blood & …, 2022 - Wiley Online Library
Background/objectives Wilms tumor (WT) is a curable type of cancer with 5‐year survival
rates of over 90% in high‐income countries, whereas this is less than 50% in low‐and …