10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis

I Mierau, M Kleerebezem - Applied microbiology and biotechnology, 2005 - Springer
Lactococcus lactis is a Gram-positive lactic acid bacterium that, in addition to its traditional
use in food fermentations, is increasingly used in modern biotechnological applications. In …

Lactococcus lactis, an Efficient Cell Factory for Recombinant Protein Production and Secretion

E Morello, LG Bermudez-Humaran, D Llull… - Journal of molecular …, 2008 - karger.com
The use of Gram-positive bacteria for heterologous protein production proves to be a useful
choice due to easy protein secretion and purification. The lactic acid bacterium Lactococcus …

[图书][B] Lactic acid bacteria: microbiological and functional aspects

S Salminen, A Von Wright - 2004 - taylorfrancis.com
While lactic acid producing fermentation has been utilized to improve the storability,
palatability, and nutritive value of perishable foods for a very long time, only recently have …

Application of enzymes for textile fibres processing

R Araujo, M Casal, A Cavaco-Paulo - Biocatalysis and …, 2008 - Taylor & Francis
This review highlights the use of enzymes in the textile industry, covering both current
commercial processes and research in this field. Amylases have been used for desizing …

Display of recombinant proteins at the surface of lactic acid bacteria: strategies and applications

C Michon, P Langella, VGH Eijsink, G Mathiesen… - Microbial cell …, 2016 - Springer
Lactic acid bacteria (LAB) are promising vectors of choice to deliver active molecules to
mucosal tissues. They are recognized as safe by the World Health Organization and some …

Protein secretion in Lactococcus lactis: an efficient way to increase the overall heterologous protein production

Y Le Loir, V Azevedo, SC Oliveira, DA Freitas… - Microbial Cell …, 2005 - Springer
Lactococcus lactis, the model lactic acid bacterium (LAB), is a food grade and well-
characterized Gram positive bacterium. It is a good candidate for heterologous protein …

Novel surface display system for proteins on non-genetically modified gram-positive bacteria

T Bosma, R Kanninga, J Neef… - Applied and …, 2006 - Am Soc Microbiol
ABSTRACT A novel display system is described that allows highly efficient immobilization of
heterologous proteins on bacterial surfaces in applications for which the use of genetically …

Serine protease inhibitors protect better than IL-10 and TGF-β anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci

LG Bermúdez-Humarán, JP Motta, C Aubry… - Microbial cell …, 2015 - Springer
Background Different studies have described the successful use of recombinant lactic acid
bacteria (recLAB) to deliver anti-inflammatory molecules at the mucosal level to treat …

Modelling strategies for the industrial exploitation of lactic acid bacteria

B Teusink, EJ Smid - Nature Reviews Microbiology, 2006 - nature.com
Lactic acid bacteria (LAB) have a long tradition of use in the food industry, and the number
and diversity of their applications has increased considerably over the years. Traditionally …

Optimization of the Lactococcus lactis nisin-controlled gene expression system NICE for industrial applications

I Mierau, K Olieman, J Mond, EJ Smid - Microbial Cell Factories, 2005 - Springer
Background The nisin-controlled gene expression system NICE of Lactococcus lactis is one
of the most widely used expression systems in Gram-positive bacteria. Despite its …