Adult neurogenesis, a complex process by which stem cells in the hippocampal brain region
differentiate and proliferate into new neurons and other resident brain cells, is known to be …

When adult neurogenesis was discovered in the mammalian brain it was often considered
an atavism and, even today, many people are convinced that there has been a …

During adult hippocampal neurogenesis, most newborn cells undergo apoptosis and are
rapidly phagocytosed by resident microglia to prevent the spillover of intracellular contents …

Specific cell populations may have unique contributions to schizophrenia but may be missed
in studies of homogenate tissue. Here laser capture microdissection followed by RNA …

The decline of brain function during aging is associated with epigenetic changes, including
DNA methylation. Lifestyle interventions can improve brain function during aging, but their …

Abstract Major Depressive Disorder (MDD) is a common psychiatric disorder for which
available medications are often not effective. The high prevalence of MDD and modest …

The generation of new neurons in the adult brain is a currently accepted phenomenon. Over
the past few decades, the subventricular zone and the hippocampal dentate gyrus have …

Hippocampal adult neurogenesis has been associated to many cognitive, emotional, and
behavioral functions and dysfunctions, and its status as a selected effect or an “appendix of …

Alzheimer's disease (AD) patients display hippocampal atrophy, memory impairment, and
cognitive decline. New neurons are generated throughout adulthood in 2 regions of the …

Adult neurogenesis enables the life‐long addition of functional neurons to the hippocampus
and is regulated by both cell‐intrinsic molecular programs and behavioral activity. De novo …