In situ self-assembly—the in situ formation of complex materials via biochemical reactions of
monomers—has enhanced the efficacy of drug delivery for cancer therapy and imaging. So …

Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Self-assembly has emerged as an extensively used method for constructing biomaterials
with sizes ranging from nanometers to micrometers. Peptides have been extensively …

In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Proteolysis targeting chimera (PROTAC) is an emerging pharmacological modality with
innovated post‐translational protein degradation capabilities. However, off‐target induced …

Materialomics integrates experiment, theory, and computation in a high‐throughput manner,
and has changed the paradigm for the research and development of new functional …

The inherent immune and metabolic tumor microenvironment (TME) of most solid tumors
adversely affect the antitumor efficacy of various treatments, which is an urgent issue to be …

Cytotoxic T lymphocytes (CTLs) are important immune cells, and their activation is a key step
for cancer immunotherapy. Precise evaluation of CTL activity in vivo provides a powerful tool …

Lung metastases are the leading cause of death among cancer patients. The challenges of
inefficient drug delivery, compounded by a robust immunosuppressive microenvironment …

As one typical intratumoral nanosynthetic medicine (INSM), in situ biosynthesized
supramolecular self-assemblies point at the accurate transformation of disordered small …