Nanoparticles‐induced potential toxicity on human health: applications, toxicity mechanisms, and evaluation models

L Xuan, Z Ju, M Skonieczna, PK Zhou, R Huang - MedComm, 2023 - Wiley Online Library
Nanoparticles (NPs) have become one of the most popular objects of scientific study during
the past decades. However, despite wealth of study reports, still there is a gap, particularly in …

The new era of nanotechnology, an alternative to change cancer treatment

A Jurj, C Braicu, LA Pop, C Tomuleasa… - Drug design …, 2017 - Taylor & Francis
In the last few years, nanostructures have gained considerable interest for the safe delivery
of therapeutic agents. Several therapeutic approaches have been reported, such as …

Co-delivery of paclitaxel and cisplatin in poly (2-oxazoline) polymeric micelles: Implications for drug loading, release, pharmacokinetics and outcome of ovarian and …

X Wan, JJ Beaudoin, N Vinod, Y Min, N Makita… - Biomaterials, 2019 - Elsevier
Concurrent delivery of multiple drugs using nanoformulations can improve outcomes of
cancer treatments. Here we demonstrate that this approach can be used to improve the …

Application of bismuth sulfide based nanomaterials in cancer diagnosis and treatment

Z Yang, L Wang, J Zhang, J Liu, X Yu - Nano Today, 2023 - Elsevier
Cancer is still the leading disease threatening human life and health at present. With the
development of nanotechnology, multifunctional nanomaterials integrated with different …

Neutrophil-mediated delivery of nanocrystal drugs via photoinduced inflammation enhances cancer therapy

Y Su, J Gao, X Dong, KA Wheeler, Z Wang - Acs Nano, 2023 - ACS Publications
The efficient delivery of anticancer agents into tumor microenvironments is critical for the
success of cancer therapies, but it is a prerequisite that drug carriers should overcome tumor …

In vitro microfluidic models of tumor microenvironment to screen transport of drugs and nanoparticles

A Ozcelikkale, H Moon, M Linnes… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
Advances in nanotechnology have enabled numerous types of nanoparticles (NPs) to
improve drug delivery to tumors. While many NP systems have been proposed, their clinical …

Translational considerations in nanomedicine: the oncology perspective

AA Gabizon, RTM de Rosales, NM La-Beck - Advanced Drug Delivery …, 2020 - Elsevier
Nanoparticles can provide effective control of the release rate and tissue distribution of their
drug payload, leading to major pharmacokinetic and pharmacodynamic changes vis-à-vis …

Distinct biodistribution of doxorubicin and the altered dispositions mediated by different liposomal formulations

R Luo, Y Li, M He, H Zhang, H Yuan, M Johnson… - International journal of …, 2017 - Elsevier
The liposomal formulations of doxorubicin produced distinct efficacy and toxicity profiles
compared to doxorubicin solution in cancer patients. This study aims to investigate the drug …

Revisiting the outstanding questions in cancer nanomedicine with a future outlook

MS Sudheesh, K Pavithran, M Sabitha - Nanoscale Advances, 2022 - pubs.rsc.org
The field of cancer nanomedicine has been fueled by the expectation of mitigating the
inefficiencies and life-threatening side effects of conventional chemotherapy. Nanomedicine …

Transport barriers and oncophysics in cancer treatment

S Nizzero, A Ziemys, M Ferrari - Trends in cancer, 2018 - cell.com
Transport processes in cancer are the focus of transport oncophysics (TOP). In the TOP
approach, the sequential negotiation of transport barriers is critical to both drug delivery and …