The diversification of cell adhesion molecules by alternative splicing is proposed to underlie
molecular codes for neuronal wiring. Transcriptomic approaches mapped detailed cell-type …

In the neocortex, fast synaptic inhibition orchestrates both spontaneous and sensory-evoked
activity. GABAergic interneurons (INs) inhibit pyramidal neurons (PNs) directly, modulating …

Adult-born granule cells (abGCs) exhibit a transient period of elevated synaptic plasticity that
plays an important role in hippocampal function. Various mechanisms have been implicated …

To better understand neural circuits and behavior, microbial opsins have been developed as
optogenetic tools for stimulating or inhibiting action potentials with high temporal and spatial …

GABAergic inhibition is critical for the precision of neuronal spiking and the homeostatic
regulation of network activity in the brain. Adult neurogenesis challenges network …

Introduction γ-Aminobutyric acid (GABA) type A receptors (GABAARs) are ligand-gated Cl-
channels that mediate the bulk of inhibitory neurotransmission in the mature CNS and are …

Pattern separation is a valuable computational function performed by neuronal circuits, such
as the dentate gyrus, where dissimilarity between inputs is increased, reducing noise and …

GABAA receptors present in extrasynaptic areas mediate tonic inhibition in hippocampal
neurons regulating the performance of neural networks. In this study, we investigated the …

Synaptic inhibition is chiefly mediated by GABAA receptors (GABAARs). GABAARs form
pentameric anion channels that typically assemble from two α, two β, and one tertiary (γ, δ, ε …

Environmental enrichment has been shown to improve hippocampus-dependent spatial
learning and memory. However, how enrichment influences hippocampal network activity …