KIR-HLA gene diversities and susceptibility to lung cancer

M Hematian Larki, E Ashouri, S Barani… - Scientific Reports, 2022 - nature.com
Killer-cell immunoglobulin-like receptors (KIR) are essential for acquiring natural killer (NK)
cell effector function, which is modulated by a balance between the net input of signals …

Coexistence of inhibitory and activating killer-cell immunoglobulin-like receptors to the same cognate HLA-C2 and Bw4 ligands confer breast cancer risk

E Ashouri, K Rajalingam, S Barani, S Farjadian… - Scientific reports, 2021 - nature.com
Human leukocyte antigen (HLA) class I-specific killer-cell immunoglobulin-like receptors
(KIR) regulate natural killer (NK) cell function in eliminating malignancy. Breast cancer (BC) …

Diversity of KIRs in invasive breast cancer patients and healthy controls along with the clinical significance in ER/PR/HER2+ patients

M Hematian Larki, S Barani, AR Talei, A Ghaderi - Genes & Immunity, 2020 - nature.com
Killer cell immunoglobulin-like receptors (KIR) consists of activating and inhibitory genes are
essential for natural killer cell education. To determine the association of KIR s with …

The effects of killer cell immunoglobulin-like receptor (KIR) genes on susceptibility to severe COVID-19 in the Iranian population

N Karami, S Barani, M Fani, S Meri, R Shafiei… - BMC immunology, 2024 - Springer
Background Variations in the innate and adaptive immune response systems are linked to
variations in the severity of COVID-19. Natural killer cell (NK) function is regulated by …

Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer

Z Shiravani, K Mirshekari, MH Larki, N Shafiee… - Journal of Reproductive …, 2024 - Elsevier
Endometrial cancer (EC) constitutes more than half of all genital cancers in women, with an
increasing incidence in different countries. Natural killer cells (NK cells) are kinds of innate …

Killer cell immunoglobulin‐like receptor (KIR) gene contents: Are they associated with cervical cancer?

AK Tembhurne, A Maheshwari, H Warke… - Journal of Medical …, 2023 - Wiley Online Library
Killer cell immunoglobulin‐like receptors (KIRs) are required for natural killer cell function
against virus‐infected cells or tumor cells. KIR gene content polymorphisms in Indian …

The impact of killer cell immunoglobulin-like receptor (KIR) genes and human leukocyte antigen (HLA) class I ligands on predisposition or protection against prostate …

MR Zamir, A Ariafar, A Ghaderi, A Amirzargar - Immunobiology, 2023 - Elsevier
Natural killer (NK) cell development largely depends on killer cell immunoglobulin-like
receptors (KIRs) and human leukocyte antigen (HLA) class I ligands. In the current study, we …

[引用][C] Killer cell immunoglobulin‐like receptor (KIR) gene distribution and allograft kidney function

E Erken, ME Senel, S Dinkci… - … Journal of Clinical …, 2021 - Wiley Online Library
Natural killer (NK) cells are an important component of innate immunity. They do not require
prior sensitisation for their cytotoxic activities. They can promote or down regulate the …