Circulating blood is filtered across the glomerular barrier to form an ultrafiltrate of plasma in
the Bowman's space. The volume of glomerular filtration adjusted by time is defined as the …

Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional …

Globally, the number of patients undergoing maintenance dialysis is increasing, yet
throughout the world there is significant variability in the practice of initiating dialysis. Factors …

The original KDIGO Clinical Practice Guideline for the Management of Blood Pressure in
Chronic Kidney Disease in the chronic kidney disease (CKD) population not receiving …

Background Change in albuminuria has strong biological plausibility as a surrogate
endpoint for progression of chronic kidney disease, but empirical evidence to support its …

Since the first description of the association between chronic kidney disease and heart
disease, many epidemiological studies have confirmed and extended this finding. As …

Background The outcomes of immunosuppressive therapy, when added to supportive care,
in patients with IgA nephropathy are uncertain. Methods We conducted a multicenter, open …

Noncommunicable diseases (NCDs) are the most common causes of premature death and
morbidity and have a major impact on health-care costs, productivity, and growth …

Chronic kidney disease is a general term for heterogeneous disorders affecting kidney
structure and function. The 2002 guidelines for definition and classification of this disease …

Fibrosis is a pathological scarring process that leads to destruction of organ architecture and
impairment of organ function. Chronic loss of organ function in most organs, including bone …