Long COVID as a tauopathy: of “Brain Fog” and “Fusogen Storms”

A Sfera, L Rahman… - International Journal of …, 2023 - mdpi.com
Long COVID, also called post-acute sequelae of SARS-CoV-2, is characterized by a
multitude of lingering symptoms, including impaired cognition, that can last for many months …

Be cool to be far: Exploiting hibernation for space exploration

M Cerri, T Hitrec, M Luppi, R Amici - Neuroscience & Biobehavioral …, 2021 - Elsevier
In mammals, torpor/hibernation is a state that is characterized by an active reduction in
metabolic rate followed by a progressive decrease in body temperature. Torpor was …

Automating cell counting in fluorescent microscopy through deep learning with c-ResUnet

R Morelli, L Clissa, R Amici, M Cerri, T Hitrec… - Scientific Reports, 2021 - nature.com
Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers
have to accomplish to assess the effects of different experimental conditions on biological …

Fluorescent Neuronal Cells v2: multi-task, multi-format annotations for deep learning in microscopy

L Clissa, A Macaluso, R Morelli, A Occhinegro… - Scientific Data, 2024 - nature.com
Abstract Fluorescent Neuronal Cells v2 is a collection of fluorescence microscopy images
and the corresponding ground-truth annotations, designed to foster innovative research in …

The aging enteric nervous system

TT Nguyen, P Baumann, O Tüscher, S Schick… - International Journal of …, 2023 - mdpi.com
The gut and the brain communicate via the nervous system, hormones, microbiota-mediated
substances, and the immune system. These intricate interactions have led to the term “gut …

Tau in the gut, does it really matter?

P Derkinderen, M Rolli‐Derkinderen… - Journal of …, 2021 - Wiley Online Library
The enteric nervous system plays a critical role in the regulation of gastrointestinal tract
functions and is often referred to as the 'second brain'because it shares many features with …

Overview of age‐related changes in psychomotor and cognitive functions in a prosimian primate, the gray mouse lemur (Microcebus murinus): Recent advances in …

Y Chaudron, F Pifferi, F Aujard - American Journal of …, 2021 - Wiley Online Library
Aging is not homogeneous in humans and the determinants leading to differences between
subjects are not fully understood. Impaired glucose homeostasis is a major risk factor for …

Localization of the serotonin transporter in the dog intestine and comparison to the rat and human intestines

R Chiocchetti, G Galiazzo, F Giancola… - Frontiers in Veterinary …, 2022 - frontiersin.org
Serotonin is crucial in gastrointestinal functions, including motility, sensitivity, secretion, and
the inflammatory response. The serotonin transporter (SERT), responsible for serotonin …

Understanding the scientific validity of synthetic torpor for radiation research and extended space missions

AP Kokko, R Chowdhury, K Sherman… - Frontiers in Space …, 2024 - frontiersin.org
The idea of synthetic torpor, an artificial state resembling the hypo-metabolic state of
torpor/hibernation, has recently gained significant scientific attention. Building on pioneering …

Sleep deprivation soon after recovery from synthetic torpor enhances tau protein dephosphorylation in the rat brain

T Hitrec, F Squarcio, E Piscitiello, M Cerri… - Journal of Comparative …, 2024 - Springer
Abstract Neuronal Tau protein hyperphosphorylation (PPtau) is a hallmark of tauopathic
neurodegeneration. However, a reversible brain PPtau occurs in mammals during either …