Entering the era of targeted therapy for chronic lymphocytic leukemia: impact on the practicing clinician

JC Byrd, JJ Jones, JA Woyach, AJ Johnson… - Journal of Clinical …, 2014 - ascopubs.org
Purpose Chemoimmunotherapy has been the standard of care for chronic lymphocytic
leukemia (CLL). However, the introduction of B-cell receptor (BCR) kinase inhibitors such as …

[HTML][HTML] Hodgkin's lymphoma in older patients: an orphan disease?

A Thyss, E Saada, L Gastaud, F Peyrade… - … Journal of Hematology …, 2014 - ncbi.nlm.nih.gov
Hodgkin Lymphoma HL can be cured in the large majority of younger patients, but prognosis
for older patients, especially those with advanced-stage disease, has not improved …

[HTML][HTML] CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic …

A Montraveta, E Lee-Vergés, J Roldán, L Jiménez… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Clinical responses to bendamustine in chronic lymphocytic leukemia (CLL) are highly
heterogeneous and no specific markers to predict sensitivity to this drug have been reported …

Outcomes of primary and secondary prophylaxis of chemotherapy-induced and febrile neutropenia in bendamustine plus rituximab regimens in patients with …

L Moore, T Bartels, DO Persky, I Abraham… - Supportive Care in …, 2021 - Springer
Purpose To examine the outcomes associated with granulocyte colony stimulating factors (G-
CSFs) administered as primary versus secondary prophylaxis in setting of bendamustine …

[HTML][HTML] Therapeutic potential of new B cell-targeted agents in the treatment of elderly and unfit patients with chronic lymphocytic leukemia

KR Rai - Journal of Hematology & Oncology, 2015 - Springer
Chronic lymphocytic leukemia (CLL), the most common adult leukemia in the Western world,
is primarily a disease of the elderly, with most patients≥ 65 years of age and having at least …

[HTML][HTML] Значение возраста и сопутствующих заболеваний в терапии хронического лимфолейкоза

ВВ Стругов, ЕА Стадник, ЮВ Вирц… - Клиническая …, 2016 - cyberleninka.ru
Актуальность и цели. Новые схемы противоопухолевой терапии хронического
лимфолейкоза (ХЛЛ) привели к улучшению показателей выживаемости относительно …

[HTML][HTML] Recent advances in the pathogenesis and treatment of chronic lymphocytic leukemia

DG Efremov, L Laurenti - Prilozi, 2014 - sciendo.com
Chronic lymphocytic leukaemia (CLL) is a common lymphoid malignancy characterized by
the expansion and progressive accumulation of mature autoreactive B lymphocytes. The …

Routine use of bendamustine in patients with chronic lymphocytic leukemia: an observational study

M Ninkovic, M Fiegl, M Mian, P Mondello… - Anticancer …, 2015 - ar.iiarjournals.org
Bendamustine is an established treatment option in chronic lymphocytic leukemia (CLL) and
frequently used in Austria and Italy. Therefore, we analyzed 100 unselected, consecutive …

[PDF][PDF] Side effects analysis based on action sets for medical treatments

H Touati, ZW Ras, J Studnicki… - Proceedings of the Third …, 2014 - di.uniba.it
Side effects result from the application of treatments to patients. They are commonly
negative and therefore undesirable. Side effects are one of the major causes of …

[HTML][HTML] Клиническая онкогематология

VV Strugov, EA Stadnik, AM Rumyantsev, TO Andreeva… - old.bloodjournal.ru
Background & Aims. The IGHV gene mutation status is a constant biological feature of tumor
cells in chronic lymphocytic leukemia (CLL). This parameter is an important predictor of the …